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Q84JD5 (P2C68_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 68

Short name=AtPP2C68
EC=3.1.3.16
Gene names
Ordered Locus Names:At5g06750
ORF Names:MPH15.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence BAB09809.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q84JD5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Probable protein phosphatase 2C 68
PRO_0000367989

Regions

Domain82 – 331250PP2C-like
Compositional bias25 – 3511Poly-Asp

Sites

Metal binding871Manganese 1 By similarity
Metal binding871Manganese 2 By similarity
Metal binding881Manganese 1; via carbonyl oxygen By similarity
Metal binding2911Manganese 2 By similarity
Metal binding3501Manganese 2 By similarity

Experimental info

Sequence conflict2681L → S in AAM61277. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: CAB959A38511D7B8

FASTA39344,140
        10         20         30         40         50         60 
MFSWLARMAL FCLRPMRRYG RMNRDDDDDD DHDGDSSSSG DSLLWSRELE RHSFGDFSIA 

        70         80         90        100        110        120 
VVQANEVIED HSQVETGNGA VFVGVYDGHG GPEASRYISD HLFSHLMRVS RERSCISEEA 

       130        140        150        160        170        180 
LRAAFSATEE GFLTLVRRTC GLKPLIAAVG SCCLVGVIWK GTLLIANVGD SRAVLGSMGS 

       190        200        210        220        230        240 
NNNRSNKIVA EQLTSDHNAA LEEVRQELRS LHPDDSHIVV LKHGVWRIKG IIQVSRSIGD 

       250        260        270        280        290        300 
AYLKRPEFSL DPSFPRFHLA EELQRPVLSA EPCVYTRVLQ TSDKFVIFAS DGLWEQMTNQ 

       310        320        330        340        350        360 
QAVEIVNKHP RPGIARRLVR RAITIAAKKR EMNYDDLKKV ERGVRRFFHD DITVVVIFID 

       370        380        390 
NELLMVEKAT VPELSIKGFS HTVGPSKFSI FLS 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. XI."
Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP002032 Genomic DNA. Translation: BAB09809.1. Different initiation.
CP002688 Genomic DNA. Translation: AED91058.1.
CP002688 Genomic DNA. Translation: AED91060.1.
BT004178 mRNA. Translation: AAO42197.1.
BT005462 mRNA. Translation: AAO63882.1.
AY084703 mRNA. Translation: AAM61277.1.
RefSeqNP_001119181.1. NM_001125709.1.
NP_568174.1. NM_120758.3.
UniGeneAt.32818.

3D structure databases

ProteinModelPortalQ84JD5.
SMRQ84JD5. Positions 71-357.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid15843. 1 interaction.
IntActQ84JD5. 1 interaction.
MINTMINT-8390464.

Proteomic databases

PaxDbQ84JD5.
PRIDEQ84JD5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G06750.1; AT5G06750.1; AT5G06750. [Q84JD5-1]
AT5G06750.3; AT5G06750.3; AT5G06750. [Q84JD5-1]
GeneID830564.
KEGGath:AT5G06750.

Organism-specific databases

TAIRAT5G06750.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000238703.
InParanoidQ84JD5.
OMAKHGVWRI.
PhylomeDBQ84JD5.
ProtClustDBCLSN2689514.

Enzyme and pathway databases

BioCycARA:AT5G06750-MONOMER.
ARA:GQT-993-MONOMER.
ARA:GQT-994-MONOMER.

Gene expression databases

GenevestigatorQ84JD5.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C68_ARATH
AccessionPrimary (citable) accession number: Q84JD5
Secondary accession number(s): Q8LFQ7, Q9FG32
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names