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Protein

Probable protein phosphatase 2C 68

Gene

At5g06750

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi87Manganese 1By similarity1
Metal bindingi87Manganese 2By similarity1
Metal bindingi88Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi291Manganese 2By similarity1
Metal bindingi350Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 68 (EC:3.1.3.16)
Short name:
AtPP2C68
Gene namesi
Ordered Locus Names:At5g06750
ORF Names:MPH15.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G06750
TAIRilocus:2170234 AT5G06750

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679891 – 393Probable protein phosphatase 2C 68Add BLAST393

Proteomic databases

PaxDbiQ84JD5

Expressioni

Gene expression databases

ExpressionAtlasiQ84JD5 baseline and differential
GenevisibleiQ84JD5 AT

Interactioni

Protein-protein interaction databases

BioGridi15843, 1 interactor
IntActiQ84JD5, 1 interactor
MINTiQ84JD5
STRINGi3702.AT5G06750.1

Structurei

3D structure databases

ProteinModelPortaliQ84JD5
SMRiQ84JD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 359PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST304

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi25 – 35Poly-AspAdd BLAST11

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0700 Eukaryota
COG0631 LUCA
HOGENOMiHOG000238703
InParanoidiQ84JD5
KOiK01102
OMAiGRMNRDD
OrthoDBiEOG09360EHR
PhylomeDBiQ84JD5

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q84JD5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFSWLARMAL FCLRPMRRYG RMNRDDDDDD DHDGDSSSSG DSLLWSRELE
60 70 80 90 100
RHSFGDFSIA VVQANEVIED HSQVETGNGA VFVGVYDGHG GPEASRYISD
110 120 130 140 150
HLFSHLMRVS RERSCISEEA LRAAFSATEE GFLTLVRRTC GLKPLIAAVG
160 170 180 190 200
SCCLVGVIWK GTLLIANVGD SRAVLGSMGS NNNRSNKIVA EQLTSDHNAA
210 220 230 240 250
LEEVRQELRS LHPDDSHIVV LKHGVWRIKG IIQVSRSIGD AYLKRPEFSL
260 270 280 290 300
DPSFPRFHLA EELQRPVLSA EPCVYTRVLQ TSDKFVIFAS DGLWEQMTNQ
310 320 330 340 350
QAVEIVNKHP RPGIARRLVR RAITIAAKKR EMNYDDLKKV ERGVRRFFHD
360 370 380 390
DITVVVIFID NELLMVEKAT VPELSIKGFS HTVGPSKFSI FLS
Length:393
Mass (Da):44,140
Last modified:June 1, 2003 - v1
Checksum:iCAB959A38511D7B8
GO

Sequence cautioni

The sequence BAB09809 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti268L → S in AAM61277 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002032 Genomic DNA Translation: BAB09809.1 Different initiation.
CP002688 Genomic DNA Translation: AED91058.1
CP002688 Genomic DNA Translation: AED91060.1
BT004178 mRNA Translation: AAO42197.1
BT005462 mRNA Translation: AAO63882.1
AY084703 mRNA Translation: AAM61277.1
RefSeqiNP_001119181.1, NM_001125709.1 [Q84JD5-1]
NP_568174.1, NM_120758.4 [Q84JD5-1]
UniGeneiAt.32818

Genome annotation databases

EnsemblPlantsiAT5G06750.1; AT5G06750.1; AT5G06750 [Q84JD5-1]
AT5G06750.3; AT5G06750.3; AT5G06750 [Q84JD5-1]
GeneIDi830564
GrameneiAT5G06750.1; AT5G06750.1; AT5G06750 [Q84JD5-1]
AT5G06750.3; AT5G06750.3; AT5G06750 [Q84JD5-1]
KEGGiath:AT5G06750

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiP2C68_ARATH
AccessioniPrimary (citable) accession number: Q84JD5
Secondary accession number(s): Q8LFQ7, Q9FG32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health