Q84II6 (Q84II6_JANS3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Terminal oxygenase component of carbazole EMBL BAC56742.1

Gene names

Name:

carAa EMBL BAC56742.1

Organism

Janthinobacterium sp. (strain J3) EMBL BAC56742.1

Taxonomic identifier

213804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Oxalobacteraceae › Janthinobacterium

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 Rieske domain. RuleBase RU004493

Ontologies

Keywords
Ligand	2Fe-2S RuleBase RU004492 PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7 Iron Iron-sulfur Metal-binding
Technical term	3D-structure PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7 PDB 3VMG PDB 3VMH PDB 3VMI
Gene Ontology (GO)
Molecular_function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	69	1	Iron-sulfur (2Fe-2S) PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	71	1	Iron-sulfur (2Fe-2S); via pros nitrogen PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	90	1	Iron-sulfur (2Fe-2S) PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	93	1	Iron-sulfur (2Fe-2S); via pros nitrogen PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	95	1	Iron-sulfur (2Fe-2S) PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	183	1	Iron; via tele nitrogen PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	187	1	Iron; via tele nitrogen PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7
	Metal binding	333	1	Iron PDB 1WW9 PDB 2DE5 PDB 2DE6 PDB 2DE7

Sequences

	Sequence		Length	Mass (Da)
	Q84II6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: D0343E77CBFB8D46	FASTA	384	43,786
	10 20 30 40 50 60 MANVDEAILK RVKGWAPYVD AKLGFRNHWY PVMFSKEINE GEPKTLKLLG ENLLVNRIDG 70 80 90 100 110 120 KLYCLKDRCL HRGVQLSVKV ECKTKSTITC WYHAWTYRWE DGVLCDILTN PTSAQIGRQK 130 140 150 160 170 180 LKTYPVQEAK GCVFIYLGDG DPPPLARDTP PNFLDDDMEI LGKNQIIKSN WRLAVENGFD 190 200 210 220 230 240 PSHIYIHKDS ILVKDNDLAL PLGFAPGGDR KQQTRVVDDD VVGRKGVYDL IGEHGVPVFE 250 260 270 280 290 300 GTIGGEVVRE GAYGEKIVAN DISIWLPGVL KVNPFPNPDM MQFEWYVPID ENTHYYFQTL 310 320 330 340 350 360 GKPCANDEER KKYEQEFESK WKPMALEGFN NDDIWAREAM VDFYADDKGW VNEILFESDE 370 380 AIVAWRKLAS EHNQGIQTQA HVSG

References

[1]	"Divergent structures of carbazole degradative car operons isolated from gram-negative bacteria." Inoue K., Widada J., Nakai S., Endoh T., Urata M., Ashikawa Y., Shintani M., Saiki Y., Yoshida T., Habe H., Omori T., Nojiri H. Biosci. Biotechnol. Biochem. 68:1467-1480(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: J3 EMBL BAC56742.1.
[2]	"Structure of the terminal oxygenase component of angular dioxygenase, carbazole 1,9a-dioxygenase." Nojiri H., Ashikawa Y., Noguchi H., Nam J.W., Urata M., Fujimoto Z., Uchimura H., Terada T., Nakamura S., Shimizu K., Yoshida T., Habe H., Omori T. J. Mol. Biol. 351:355-370(2005) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH IRON AND IRON-SULFUR (2FE-2S).
[3]	"Electron transfer complex formation between oxygenase and ferredoxin components in Rieske nonheme iron oxygenase system." Ashikawa Y., Fujimoto Z., Noguchi H., Habe H., Omori T., Yamane H., Nojiri H. Structure 14:1779-1789(2006) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH IRON AND IRON-SULFUR (2FE-2S).
[4]	"Structural insight into the substrate- and dioxygen-binding manner in the catalytic cycle of rieske nonheme iron oxygenase system, carbazole 1,9a-dioxygenase." Ashikawa Y., Fujimoto Z., Usami Y., Inoue K., Noguchi H., Yamane H., Nojiri H. BMC Struct. Biol. 12:15-15(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AB095952 Genomic DNA. Translation: BAC56742.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1WW9	X-ray	1.95	A	1-384	[»]
2DE5	X-ray	1.90	A/B/C	1-384	[»]
2DE6	X-ray	1.80	A/B/C	1-384	[»]
2DE7	X-ray	2.00	A/B/C	1-384	[»]
3VMG	X-ray	1.95	A/B/C	1-384	[»]
3VMH	X-ray	1.85	A/B/C	1-384	[»]
3VMI	X-ray	2.00	A/B/C	1-384	[»]

ProteinModelPortal

Q84II6.

SMR

Q84II6. Positions 1-384.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-29167N.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.102.10.10. 1 hit.

InterPro

IPR021028. Homotrim_ring_OHase_catalytic.
IPR017941. Rieske_2Fe-2S.
[Graphical view]

Pfam

PF11723. Aromatic_hydrox. 1 hit.
PF00355. Rieske. 1 hit.
[Graphical view]

SUPFAM

SSF50022. Rieske_dom. 1 hit.

PROSITE

PS51296. RIESKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q84II6.

Entry information

Entry name

Q84II6_JANS3

Accession

Primary (citable) accession number: Q84II6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	March 6, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)