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Q84HB8

- Q84HB8_STRCZ

UniProt

Q84HB8 - Q84HB8_STRCZ

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Protein
Submitted name:

Epoxide hydrolase

Gene
N/A
Organism
Streptomyces carzinostaticus subsp. neocarzinostaticus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei174 – 1741Acetate 1Imported
Binding sitei178 – 1781Acetate 2Imported
Binding sitei200 – 2001Acetate 2; via amide nitrogenImported

GO - Molecular functioni

  1. cis-stilbene-oxide hydrolase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Epoxide hydrolaseImported
OrganismiStreptomyces carzinostaticus subsp. neocarzinostaticusImported
Taxonomic identifieri167636 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4I19X-ray2.15A1-385[»]
4QA9X-ray1.56A1-385[»]
ProteinModelPortaliQ84HB8.

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
IPR010497. Epoxide_hydro_N.
IPR016292. Epoxide_hydrolase.
[Graphical view]
PfamiPF06441. EHN. 1 hit.
[Graphical view]
PIRSFiPIRSF001112. Epoxide_hydrolase. 1 hit.
PRINTSiPR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q84HB8-1 [UniParc]FASTAAdd to Basket

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MRPFQVQIPQ ADIDDLKRRL SETRWPELVD VGWSRGAPLS YIKELAEYWR    50
DGFDWRAAER RINQYPQFTT EIDGATIHFL HVRSPEPDAT PMVITHGWPG 100
TPVEFLDIIG PLTDPRAHGG DPADAFHLVI PSLPGFGLSG PLKSAGWELG 150
RIAMAWSKLM ASLGYERYIA QGGDIGAFTS LLLGAIDPSH LAGIHVNLLQ 200
TNLSGEPGEL ETLSDADKAR LAVSERFLDD LSGPMKMQST RPHTIGYMLN 250
DSPVAQLAYL LEMFKHWAQT ENVPEDAVDR DLMLTHISLF WFTATGGSAA 300
QAHYELKPFL PITSLIGRSP TLDVPMGVAV YPGALFQPVR SLAERDFKQI 350
VHWAELDRGG HFSAMEEPDL FVDDLRTFNR TLKKL 385
Length:385
Mass (Da):42,907
Last modified:June 1, 2003 - v1
Checksum:i41F31C25B54AAF74
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY117439 Genomic DNA. Translation: AAM77995.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY117439 Genomic DNA. Translation: AAM77995.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4I19 X-ray 2.15 A 1-385 [» ]
4QA9 X-ray 1.56 A 1-385 [» ]
ProteinModelPortali Q84HB8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
IPR010497. Epoxide_hydro_N.
IPR016292. Epoxide_hydrolase.
[Graphical view ]
Pfami PF06441. EHN. 1 hit.
[Graphical view ]
PIRSFi PIRSF001112. Epoxide_hydrolase. 1 hit.
PRINTSi PR00412. EPOXHYDRLASE.
SUPFAMi SSF53474. SSF53474. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases."
    Liu W., Nonaka K., Nie L., Zhang J., Christenson S.D., Bae J., Van Lanen S.G., Zazopoulos E., Farnet C.M., Yang C.F., Shen B.
    Chem. Biol. 12:293-302(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 15944Imported.
  2. "The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus."
    Tan K., Bigelow L., Clancy S., Babnigg G., Bingman C.A., Yennamalli R., Lohman J., Ma M., Shen B., Phillips Jr. G.N., Joachimiak A.
    Submitted (NOV-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS).
  3. "Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus."
    Wang F., Tan K., Bigelow L., Clancy S., Babnigg G., Bingman C.A., Yennamalli R., Lohman J., Ma M., Shen B., Joachimiak A., Phillips Jr. G.N.
    Submitted (MAY-2014) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.56 ANGSTROMS).

Entry informationi

Entry nameiQ84HB8_STRCZ
AccessioniPrimary (citable) accession number: Q84HB8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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