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Q84HB8

- Q84HB8_STRCZ

UniProt

Q84HB8 - Q84HB8_STRCZ

Protein
Submitted name:

Epoxide hydrolase

Gene
N/A
Organism
Streptomyces carzinostaticus subsp. neocarzinostaticus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei174 – 1741Acetate 1Imported
    Binding sitei178 – 1781Acetate 2Imported
    Binding sitei200 – 2001Acetate 2; via amide nitrogenImported

    GO - Molecular functioni

    1. cis-stilbene-oxide hydrolase activity Source: InterPro

    Keywords - Molecular functioni

    HydrolaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Epoxide hydrolaseImported
    OrganismiStreptomyces carzinostaticus subsp. neocarzinostaticusImported
    Taxonomic identifieri167636 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4I19X-ray2.15A1-385[»]
    4QA9X-ray1.56A1-385[»]
    ProteinModelPortaliQ84HB8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR000639. Epox_hydrolase-like.
    IPR010497. Epoxide_hydro_N.
    IPR016292. Epoxide_hydrolase.
    [Graphical view]
    PfamiPF06441. EHN. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001112. Epoxide_hydrolase. 1 hit.
    PRINTSiPR00412. EPOXHYDRLASE.
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q84HB8-1 [UniParc]FASTAAdd to Basket

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    MRPFQVQIPQ ADIDDLKRRL SETRWPELVD VGWSRGAPLS YIKELAEYWR    50
    DGFDWRAAER RINQYPQFTT EIDGATIHFL HVRSPEPDAT PMVITHGWPG 100
    TPVEFLDIIG PLTDPRAHGG DPADAFHLVI PSLPGFGLSG PLKSAGWELG 150
    RIAMAWSKLM ASLGYERYIA QGGDIGAFTS LLLGAIDPSH LAGIHVNLLQ 200
    TNLSGEPGEL ETLSDADKAR LAVSERFLDD LSGPMKMQST RPHTIGYMLN 250
    DSPVAQLAYL LEMFKHWAQT ENVPEDAVDR DLMLTHISLF WFTATGGSAA 300
    QAHYELKPFL PITSLIGRSP TLDVPMGVAV YPGALFQPVR SLAERDFKQI 350
    VHWAELDRGG HFSAMEEPDL FVDDLRTFNR TLKKL 385
    Length:385
    Mass (Da):42,907
    Last modified:June 1, 2003 - v1
    Checksum:i41F31C25B54AAF74
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY117439 Genomic DNA. Translation: AAM77995.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY117439 Genomic DNA. Translation: AAM77995.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4I19 X-ray 2.15 A 1-385 [» ]
    4QA9 X-ray 1.56 A 1-385 [» ]
    ProteinModelPortali Q84HB8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR000639. Epox_hydrolase-like.
    IPR010497. Epoxide_hydro_N.
    IPR016292. Epoxide_hydrolase.
    [Graphical view ]
    Pfami PF06441. EHN. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001112. Epoxide_hydrolase. 1 hit.
    PRINTSi PR00412. EPOXHYDRLASE.
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases."
      Liu W., Nonaka K., Nie L., Zhang J., Christenson S.D., Bae J., Van Lanen S.G., Zazopoulos E., Farnet C.M., Yang C.F., Shen B.
      Chem. Biol. 12:293-302(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ATCC 15944Imported.
    2. "The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus."
      Tan K., Bigelow L., Clancy S., Babnigg G., Bingman C.A., Yennamalli R., Lohman J., Ma M., Shen B., Phillips Jr. G.N., Joachimiak A.
      Submitted (NOV-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS).
    3. "Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus."
      Wang F., Tan K., Bigelow L., Clancy S., Babnigg G., Bingman C.A., Yennamalli R., Lohman J., Ma M., Shen B., Joachimiak A., Phillips Jr. G.N.
      Submitted (MAY-2014) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.56 ANGSTROMS).

    Entry informationi

    Entry nameiQ84HB8_STRCZ
    AccessioniPrimary (citable) accession number: Q84HB8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3