Q84F86 (NAGA_LYSSH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-acetylglucosamine-6-phosphate deacetylase
EC=3.5.1.25

Alternative name(s):
GlcNAc 6-P deacetylase

Gene names

Name:

nagA

Organism

Lysinibacillus sphaericus (Bacillus sphaericus)

Taxonomic identifier

1421 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Pathway	Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 4/5.
Induction	By N-acetylglucosamine.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 387	387	N-acetylglucosamine-6-phosphate deacetylase		PRO_0000170913

Sequences

	Sequence		Length	Mass (Da)
	Q84F86 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A7814358BE311857	FASTA	387	42,382
	10 20 30 40 50 60 MFFLSLIIRN ITVVNASGRD EQMDVWMKDG KIAQIAQHIH AQGVDQLEGS GKFLLPGFID 70 80 90 100 110 120 MHIHGSAQMD TMDASDEGLH IHGPITIKEG TTSFLATTMT QSFDWFDRAQ RQCGNNFSPK 130 140 150 160 170 180 SDEAEVLGLH IEGPFVSKQR AGAQPLDYIV QPDMEVIKKW QALSGQKIKQ ITLAPEEPNG 190 200 210 220 230 240 MAAVQSLSES GVIVSIGHSD ATFEQMQEAV QLGASQGTHL YNQMRPFHHR DPGVVGGVLL 250 260 270 280 290 300 VDAIKAELIV DFIHMHEGAV EMAYRLKGAD GIILITDAMR AKGMPYGEYD LGGQLVHVTE 310 320 330 340 350 360 SGAHLSNGSL AGSILTMDQA VRNMRQITNC TLEELVKMSS YNAAQQLKLT NKGQLTEGYD 370 380 ADAVIVDEHL LLHQTIKAGR IRVQTNN

References

[1]	"Phosphoenolpyruvate phosphotransferase system and N-acetylglucosamine metabolism in Bacillus sphaericus." Alice A.F., Perez-Martinez G., Sanchez-Rivas C. Microbiology 149:1687-1698(2003) [PubMed: 12855720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 2362.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY211495 Genomic DNA. Translation: AAO43396.1.
3D structure databases
ProteinModelPortal	Q84F86.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMs	TIGR00221. NagA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NAGA_LYSSH

Accession

Primary (citable) accession number: Q84F86

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	September 21, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program