Reviewed, UniProtKB/Swiss-Prot Q84F86 (NAGA_BACSH)

Names and origin

Protein names

Recommended name:
    N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase

Gene names

Name:

nagA

Organism

Bacillus sphaericus

Taxonomic identifier

1421 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Planococcaceae › Lysinibacillus

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Pathway	Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 4/5.
Induction	By N-acetylglucosamine.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 387	387	N-acetylglucosamine-6-phosphate deacetylase		PRO_0000170913

Sequences

	Sequence		Length	Mass (Da)
	Q84F86-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A7814358BE311857	FASTA	387	42,382
	10 20 30 40 50 60 MFFLSLIIRN ITVVNASGRD EQMDVWMKDG KIAQIAQHIH AQGVDQLEGS GKFLLPGFID 70 80 90 100 110 120 MHIHGSAQMD TMDASDEGLH IHGPITIKEG TTSFLATTMT QSFDWFDRAQ RQCGNNFSPK 130 140 150 160 170 180 SDEAEVLGLH IEGPFVSKQR AGAQPLDYIV QPDMEVIKKW QALSGQKIKQ ITLAPEEPNG 190 200 210 220 230 240 MAAVQSLSES GVIVSIGHSD ATFEQMQEAV QLGASQGTHL YNQMRPFHHR DPGVVGGVLL 250 260 270 280 290 300 VDAIKAELIV DFIHMHEGAV EMAYRLKGAD GIILITDAMR AKGMPYGEYD LGGQLVHVTE 310 320 330 340 350 360 SGAHLSNGSL AGSILTMDQA VRNMRQITNC TLEELVKMSS YNAAQQLKLT NKGQLTEGYD 370 380 ADAVIVDEHL LLHQTIKAGR IRVQTNN

References

[1]	"Phosphoenolpyruvate phosphotransferase system and N-acetylglucosamine metabolism in Bacillus sphaericus." Alice A.F., Perez-Martinez G., Sanchez-Rivas C. Microbiology 149:1687-1698(2003) [PubMed: 12855720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 2362.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY211495 Genomic DNA. Translation: AAO43396.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	3.5.1.25. 327.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00221. nagA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NAGA_BACSH

Accession

Primary (citable) accession number: Q84F86

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)