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Protein

Ribosomal protein L11 methyltransferase

Gene

prmA

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Methylates ribosomal protein L11; this reaction probably occurs before the protein is assembled into the ribosome. This function is dispensable for growth and thermostability.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-686-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal protein L11 methyltransferase (EC:2.1.1.-)
Short name:
L11 Mtase
Gene namesi
Name:prmA
Ordered Locus Names:TTHA0656
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Ribosomal protein L11 methyltransferasePRO_0000192328Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-44643N.
IntActiQ84BQ9. 1 interaction.
MINTiMINT-4299402.
STRINGi300852.TTHA0656.

Structurei

Secondary structure

1
254
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 87Combined sources
Turni10 – 134Combined sources
Helixi14 – 163Combined sources
Helixi17 – 226Combined sources
Beta strandi27 – 315Combined sources
Beta strandi34 – 418Combined sources
Beta strandi50 – 534Combined sources
Helixi56 – 6611Combined sources
Beta strandi70 – 723Combined sources
Beta strandi75 – 784Combined sources
Beta strandi86 – 927Combined sources
Beta strandi97 – 993Combined sources
Helixi105 – 11713Combined sources
Beta strandi123 – 1286Combined sources
Helixi133 – 1408Combined sources
Beta strandi144 – 1507Combined sources
Helixi152 – 1543Combined sources
Helixi155 – 16410Combined sources
Beta strandi170 – 1745Combined sources
Helixi176 – 1794Combined sources
Helixi180 – 1823Combined sources
Beta strandi185 – 1917Combined sources
Helixi194 – 20714Combined sources
Beta strandi208 – 22013Combined sources
Helixi221 – 2233Combined sources
Helixi224 – 23310Combined sources
Beta strandi237 – 2448Combined sources
Beta strandi247 – 2537Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1UFKX-ray1.90A1-254[»]
2NXCX-ray1.59A1-254[»]
2NXEX-ray1.75A/B1-254[»]
2NXJX-ray2.30A/B1-254[»]
2NXNX-ray2.40A1-254[»]
2ZBPX-ray2.30A1-254[»]
2ZBQX-ray2.40A1-254[»]
2ZBRX-ray1.90A1-254[»]
3CJQX-ray2.70A/D/G1-254[»]
3CJRX-ray2.05A1-254[»]
3CJSX-ray1.37A1-59[»]
3CJTX-ray2.30A/C/E/G/I/K/M/O1-254[»]
3EGVX-ray1.75A1-254[»]
ProteinModelPortaliQ84BQ9.
SMRiQ84BQ9. Positions 1-254.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ84BQ9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105F59. Bacteria.
COG2264. LUCA.
HOGENOMiHOG000007391.
KOiK02687.
OMAiHHATTYL.
PhylomeDBiQ84BQ9.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00735. Methyltr_PrmA. 1 hit.
InterProiIPR004498. Ribosomal_PrmA_MeTrfase.
IPR029063. SAM-dependent_MTases.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q84BQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWVYRLKGTL EALDPILPGL FDGGARGLWE REGEVWAFFP APVDLPYEGV
60 70 80 90 100
WEEVGDEDWL EAWRRDLKPA LAPPFVVLAP WHTWEGAEIP LVIEPGMAFG
110 120 130 140 150
TGHHETTRLA LKALARHLRP GDKVLDLGTG SGVLAIAAEK LGGKALGVDI
160 170 180 190 200
DPMVLPQAEA NAKRNGVRPR FLEGSLEAAL PFGPFDLLVA NLYAELHAAL
210 220 230 240 250
APRYREALVP GGRALLTGIL KDRAPLVREA MAGAGFRPLE EAAEGEWVLL

AYGR
Length:254
Mass (Da):27,631
Last modified:March 29, 2005 - v2
Checksum:iD33A79573F360946
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti225 – 2251P → S in BAC67244 (PubMed:12777815).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB103400 Genomic DNA. Translation: BAC67244.1.
AP008226 Genomic DNA. Translation: BAD70479.1.
RefSeqiWP_011228100.1. NC_006461.1.
YP_143922.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70479; BAD70479; BAD70479.
GeneIDi3168879.
KEGGittj:TTHA0656.
PATRICi23956289. VBITheThe93045_0650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB103400 Genomic DNA. Translation: BAC67244.1.
AP008226 Genomic DNA. Translation: BAD70479.1.
RefSeqiWP_011228100.1. NC_006461.1.
YP_143922.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1UFKX-ray1.90A1-254[»]
2NXCX-ray1.59A1-254[»]
2NXEX-ray1.75A/B1-254[»]
2NXJX-ray2.30A/B1-254[»]
2NXNX-ray2.40A1-254[»]
2ZBPX-ray2.30A1-254[»]
2ZBQX-ray2.40A1-254[»]
2ZBRX-ray1.90A1-254[»]
3CJQX-ray2.70A/D/G1-254[»]
3CJRX-ray2.05A1-254[»]
3CJSX-ray1.37A1-59[»]
3CJTX-ray2.30A/C/E/G/I/K/M/O1-254[»]
3EGVX-ray1.75A1-254[»]
ProteinModelPortaliQ84BQ9.
SMRiQ84BQ9. Positions 1-254.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-44643N.
IntActiQ84BQ9. 1 interaction.
MINTiMINT-4299402.
STRINGi300852.TTHA0656.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70479; BAD70479; BAD70479.
GeneIDi3168879.
KEGGittj:TTHA0656.
PATRICi23956289. VBITheThe93045_0650.

Phylogenomic databases

eggNOGiENOG4105F59. Bacteria.
COG2264. LUCA.
HOGENOMiHOG000007391.
KOiK02687.
OMAiHHATTYL.
PhylomeDBiQ84BQ9.

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-686-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ84BQ9.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00735. Methyltr_PrmA. 1 hit.
InterProiIPR004498. Ribosomal_PrmA_MeTrfase.
IPR029063. SAM-dependent_MTases.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPRMA_THET8
AccessioniPrimary (citable) accession number: Q84BQ9
Secondary accession number(s): Q5SKI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 29, 2005
Last modified: September 7, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.