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Protein

Ribosomal protein L11 methyltransferase

Gene

prmA

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Methylates ribosomal protein L11; this reaction probably occurs before the protein is assembled into the ribosome. This function is dispensable for growth and thermostability.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal protein L11 methyltransferase (EC:2.1.1.-)
Short name:
L11 Mtase
Gene namesi
Name:prmA
Ordered Locus Names:TTHA0656
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001923281 – 254Ribosomal protein L11 methyltransferaseAdd BLAST254

Interactioni

Protein-protein interaction databases

DIPiDIP-44643N.
IntActiQ84BQ9. 1 interactor.
MINTiMINT-4299402.
STRINGi300852.TTHA0656.

Structurei

Secondary structure

1254
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 8Combined sources7
Turni10 – 13Combined sources4
Helixi14 – 16Combined sources3
Helixi17 – 22Combined sources6
Beta strandi27 – 31Combined sources5
Beta strandi34 – 41Combined sources8
Beta strandi50 – 53Combined sources4
Helixi56 – 66Combined sources11
Beta strandi70 – 72Combined sources3
Beta strandi75 – 78Combined sources4
Beta strandi86 – 92Combined sources7
Beta strandi97 – 99Combined sources3
Helixi105 – 117Combined sources13
Beta strandi123 – 128Combined sources6
Helixi133 – 140Combined sources8
Beta strandi144 – 150Combined sources7
Helixi152 – 154Combined sources3
Helixi155 – 164Combined sources10
Beta strandi170 – 174Combined sources5
Helixi176 – 179Combined sources4
Helixi180 – 182Combined sources3
Beta strandi185 – 191Combined sources7
Helixi194 – 207Combined sources14
Beta strandi208 – 220Combined sources13
Helixi221 – 223Combined sources3
Helixi224 – 233Combined sources10
Beta strandi237 – 244Combined sources8
Beta strandi247 – 253Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UFKX-ray1.90A1-254[»]
2NXCX-ray1.59A1-254[»]
2NXEX-ray1.75A/B1-254[»]
2NXJX-ray2.30A/B1-254[»]
2NXNX-ray2.40A1-254[»]
2ZBPX-ray2.30A1-254[»]
2ZBQX-ray2.40A1-254[»]
2ZBRX-ray1.90A1-254[»]
3CJQX-ray2.70A/D/G1-254[»]
3CJRX-ray2.05A1-254[»]
3CJSX-ray1.37A1-59[»]
3CJTX-ray2.30A/C/E/G/I/K/M/O1-254[»]
3EGVX-ray1.75A1-254[»]
ProteinModelPortaliQ84BQ9.
SMRiQ84BQ9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ84BQ9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105F59. Bacteria.
COG2264. LUCA.
HOGENOMiHOG000007391.
KOiK02687.
OMAiHHATTYL.
PhylomeDBiQ84BQ9.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00735. Methyltr_PrmA. 1 hit.
InterProiIPR004498. Ribosomal_PrmA_MeTrfase.
IPR029063. SAM-dependent_MTases.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q84BQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWVYRLKGTL EALDPILPGL FDGGARGLWE REGEVWAFFP APVDLPYEGV
60 70 80 90 100
WEEVGDEDWL EAWRRDLKPA LAPPFVVLAP WHTWEGAEIP LVIEPGMAFG
110 120 130 140 150
TGHHETTRLA LKALARHLRP GDKVLDLGTG SGVLAIAAEK LGGKALGVDI
160 170 180 190 200
DPMVLPQAEA NAKRNGVRPR FLEGSLEAAL PFGPFDLLVA NLYAELHAAL
210 220 230 240 250
APRYREALVP GGRALLTGIL KDRAPLVREA MAGAGFRPLE EAAEGEWVLL

AYGR
Length:254
Mass (Da):27,631
Last modified:March 29, 2005 - v2
Checksum:iD33A79573F360946
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti225P → S in BAC67244 (PubMed:12777815).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB103400 Genomic DNA. Translation: BAC67244.1.
AP008226 Genomic DNA. Translation: BAD70479.1.
RefSeqiWP_011228100.1. NC_006461.1.
YP_143922.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70479; BAD70479; BAD70479.
GeneIDi3168879.
KEGGittj:TTHA0656.
PATRICi23956289. VBITheThe93045_0650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB103400 Genomic DNA. Translation: BAC67244.1.
AP008226 Genomic DNA. Translation: BAD70479.1.
RefSeqiWP_011228100.1. NC_006461.1.
YP_143922.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UFKX-ray1.90A1-254[»]
2NXCX-ray1.59A1-254[»]
2NXEX-ray1.75A/B1-254[»]
2NXJX-ray2.30A/B1-254[»]
2NXNX-ray2.40A1-254[»]
2ZBPX-ray2.30A1-254[»]
2ZBQX-ray2.40A1-254[»]
2ZBRX-ray1.90A1-254[»]
3CJQX-ray2.70A/D/G1-254[»]
3CJRX-ray2.05A1-254[»]
3CJSX-ray1.37A1-59[»]
3CJTX-ray2.30A/C/E/G/I/K/M/O1-254[»]
3EGVX-ray1.75A1-254[»]
ProteinModelPortaliQ84BQ9.
SMRiQ84BQ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-44643N.
IntActiQ84BQ9. 1 interactor.
MINTiMINT-4299402.
STRINGi300852.TTHA0656.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70479; BAD70479; BAD70479.
GeneIDi3168879.
KEGGittj:TTHA0656.
PATRICi23956289. VBITheThe93045_0650.

Phylogenomic databases

eggNOGiENOG4105F59. Bacteria.
COG2264. LUCA.
HOGENOMiHOG000007391.
KOiK02687.
OMAiHHATTYL.
PhylomeDBiQ84BQ9.

Miscellaneous databases

EvolutionaryTraceiQ84BQ9.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00735. Methyltr_PrmA. 1 hit.
InterProiIPR004498. Ribosomal_PrmA_MeTrfase.
IPR029063. SAM-dependent_MTases.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPRMA_THET8
AccessioniPrimary (citable) accession number: Q84BQ9
Secondary accession number(s): Q5SKI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 29, 2005
Last modified: November 2, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.