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Protein
Submitted name:

Iron-regulated outer membrane protein

Gene

fetA

Organism
Neisseria meningitidis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. receptor activity Source: InterPro

GO - Biological processi

  1. siderophore transport Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Iron-regulated outer membrane proteinImported
Gene namesi
Name:fetAImported
OrganismiNeisseria meningitidisImported
Taxonomic identifieri487 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Subcellular locationi

  1. Cell outer membrane UniRule annotation

GO - Cellular componenti

  1. cell outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

MembraneUniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B7OX-ray2.32A1-672[»]
ProteinModelPortaliQ841A2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TonB-dependent receptor family.UniRule annotation

Keywords - Domaini

TonB boxUniRule annotation

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01783. TonB-siderophor. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q841A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VLDTVTVKGD RQGSKIRTNI VTLQQKDEST ATDMRELLKE EPSIDFGGGN
60 70 80 90 100
GTSQFLTLRG MGQNSVDIKV DNAYSDSQIL YHQGRFIVDP ALVKVVSVQK
110 120 130 140 150
GAGSASAGIG ATNGAIIAKT VDAQDLLKGL DKNWGVRLNS GFASNEGVSY
160 170 180 190 200
GASVFGKEGN FDGLFSYNRN DEKEYEAGKG FRNFNGGKTV PYSALDKRSY
210 220 230 240 250
LAKIGTTFGD GDHRIVLSHM KDQHRGIRTV REEFTVGDAS SRTNITRQAP
260 270 280 290 300
SYRETTQSNT NLAYTGKDLG FVEKLDANAY VLEKKRYSAD DKDNGYAGNV
310 320 330 340 350
VGPNHTRITT RGMNFNFDSR LAEQTLLKYG INYRHQEIKP QAFLNGEFEI
360 370 380 390 400
SGKKKDPKDP KKEIDKTDEE KAKDKKDMDL VHSYKLSNPT KTDTGAYIEA
410 420 430 440 450
IHELDGFTLT GGLRYDRFKV KTHDGKTVSS SNLNPSFGVI WQPHEHWSFS
460 470 480 490 500
SSHNYASRSP RLYDALQTHG KRGIISIADG TKAERARNTE IGFNYNDGTF
510 520 530 540 550
AANGSYFWQT IKDALANPQN RHVSAAVREA VNAGYIKNHG YELGASYRTG
560 570 580 590 600
GLTAKVGVSH SKPRFYDTHP KKLLSANPEF GAQVGRTWTA SLAYRFQNPN
610 620 630 640 650
LEIGWRGRYV QKAVGSILVA GQKDRNGKLE NVVRKGFGVN DVFANWKPLG
660 670
KDTLNVNLSV NNVFNTFYYP HS
Length:672
Mass (Da):74,401
Last modified:June 1, 2003 - v1
Checksum:iC64E1F5BA541261F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei672 – 6721Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF439239 Genomic DNA. Translation: AAP12817.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF439239 Genomic DNA. Translation: AAP12817.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B7OX-ray2.32A1-672[»]
ProteinModelPortaliQ841A2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01783. TonB-siderophor. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Antigenic diversity of meningococcal enterobactin receptor FetA, a vaccine component."
    Thompson E.A., Feavers I.M., Maiden M.C.
    Microbiology 149:1849-1858(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Z4756Imported.
  2. "Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis."
    Saleem M., Prince S.M., Rigby S.E., Imran M., Patel H., Chan H., Sanders H., Maiden M.C., Feavers I.M., Derrick J.P.
    PLoS ONE 8:e56746-e56746(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.32 ANGSTROMS).

Entry informationi

Entry nameiQ841A2_NEIME
AccessioniPrimary (citable) accession number: Q841A2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 4, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.