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Q841A2

- Q841A2_NEIME

UniProt

Q841A2 - Q841A2_NEIME

Protein
Submitted name:

Iron-regulated outer membrane protein

Gene

fetA

Organism
Neisseria meningitidis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. receptor activity Source: InterPro
    3. siderophore transmembrane transporter activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Iron-regulated outer membrane proteinImported
    Gene namesi
    Name:fetAImported
    OrganismiNeisseria meningitidisImported
    Taxonomic identifieri487 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

    Subcellular locationi

    Cell outer membrane UniRule annotation

    GO - Cellular componenti

    1. cell outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    MembraneUniRule annotation

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4B7OX-ray2.32A1-672[»]
    ProteinModelPortaliQ841A2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TonB-dependent receptor family.UniRule annotation

    Keywords - Domaini

    TonB boxUniRule annotation

    Family and domain databases

    Gene3Di2.170.130.10. 1 hit.
    2.40.170.20. 1 hit.
    InterProiIPR012910. Plug.
    IPR000531. TonB-dep_rcpt_b-brl.
    IPR010105. TonB_sidphr_rcpt.
    [Graphical view]
    PfamiPF07715. Plug. 1 hit.
    PF00593. TonB_dep_Rec. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01783. TonB-siderophor. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q841A2-1 [UniParc]FASTAAdd to Basket

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    VLDTVTVKGD RQGSKIRTNI VTLQQKDEST ATDMRELLKE EPSIDFGGGN    50
    GTSQFLTLRG MGQNSVDIKV DNAYSDSQIL YHQGRFIVDP ALVKVVSVQK 100
    GAGSASAGIG ATNGAIIAKT VDAQDLLKGL DKNWGVRLNS GFASNEGVSY 150
    GASVFGKEGN FDGLFSYNRN DEKEYEAGKG FRNFNGGKTV PYSALDKRSY 200
    LAKIGTTFGD GDHRIVLSHM KDQHRGIRTV REEFTVGDAS SRTNITRQAP 250
    SYRETTQSNT NLAYTGKDLG FVEKLDANAY VLEKKRYSAD DKDNGYAGNV 300
    VGPNHTRITT RGMNFNFDSR LAEQTLLKYG INYRHQEIKP QAFLNGEFEI 350
    SGKKKDPKDP KKEIDKTDEE KAKDKKDMDL VHSYKLSNPT KTDTGAYIEA 400
    IHELDGFTLT GGLRYDRFKV KTHDGKTVSS SNLNPSFGVI WQPHEHWSFS 450
    SSHNYASRSP RLYDALQTHG KRGIISIADG TKAERARNTE IGFNYNDGTF 500
    AANGSYFWQT IKDALANPQN RHVSAAVREA VNAGYIKNHG YELGASYRTG 550
    GLTAKVGVSH SKPRFYDTHP KKLLSANPEF GAQVGRTWTA SLAYRFQNPN 600
    LEIGWRGRYV QKAVGSILVA GQKDRNGKLE NVVRKGFGVN DVFANWKPLG 650
    KDTLNVNLSV NNVFNTFYYP HS 672
    Length:672
    Mass (Da):74,401
    Last modified:June 1, 2003 - v1
    Checksum:iC64E1F5BA541261F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei672 – 6721Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF439239 Genomic DNA. Translation: AAP12817.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF439239 Genomic DNA. Translation: AAP12817.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4B7O X-ray 2.32 A 1-672 [» ]
    ProteinModelPortali Q841A2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.170.130.10. 1 hit.
    2.40.170.20. 1 hit.
    InterProi IPR012910. Plug.
    IPR000531. TonB-dep_rcpt_b-brl.
    IPR010105. TonB_sidphr_rcpt.
    [Graphical view ]
    Pfami PF07715. Plug. 1 hit.
    PF00593. TonB_dep_Rec. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01783. TonB-siderophor. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Antigenic diversity of meningococcal enterobactin receptor FetA, a vaccine component."
      Thompson E.A., Feavers I.M., Maiden M.C.
      Microbiology 149:1849-1858(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Z4756Imported.
    2. "Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis."
      Saleem M., Prince S.M., Rigby S.E., Imran M., Patel H., Chan H., Sanders H., Maiden M.C., Feavers I.M., Derrick J.P.
      PLoS ONE 8:e56746-e56746(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.32 ANGSTROMS).

    Entry informationi

    Entry nameiQ841A2_NEIME
    AccessioniPrimary (citable) accession number: Q841A2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3