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Q83SG7 (ACPH_SHIFL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative acyl carrier protein phosphodiesterase

Short name=ACP phosphodiesterase
EC=3.1.4.14
Gene names
Name:acpH
Ordered Locus Names:SF0341, S0349
OrganismShigella flexneri [Complete proteome] [HAMAP]
Taxonomic identifier623 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella

Protein attributes

Sequence length143 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity.

Catalytic activity

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].

Sequence similarities

Belongs to the AcpH family.

Caution

Could be the product of a pseudogene. The N-terminus is shorter than in related proteins.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_function[acyl-carrier-protein] phosphodiesterase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 143143Putative acyl carrier protein phosphodiesterase
PRO_0000226276

Sequences

Sequence LengthMass (Da)Tools
Q83SG7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: A0731A290EB3F83D

FASTA14317,418
        10         20         30         40         50         60 
MTDNLPEVRE AQEWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM 

        70         80         90        100        110        120 
TILPDSPPRF INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLDAHY 

       130        140 
DALETRFWQF YPRMMAQASH KAL 

« Hide

References

[1]"Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157."
Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y. expand/collapse author list , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.
Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 301 / Serotype 2a.
[2]"Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T."
Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.
Infect. Immun. 71:2775-2786(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700930 / 2457T / Serotype 2a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005674 Genomic DNA. Translation: AAN41999.1.
AE014073 Genomic DNA. No translation available.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198214.SF0341.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN41999; AAN41999; SF0341.
PATRIC18712285. VBIShiFle86970_0391.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3124.
HOGENOMHOG000275880.
OMARIRFANS.
OrthoDBEOG6K6V7H.
ProtClustDBCLSK384313.

Family and domain databases

InterProIPR007431. ACP_phosphodiesterase.
[Graphical view]
PfamPF04336. DUF479. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACPH_SHIFL
AccessionPrimary (citable) accession number: Q83SG7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families