Q83SG7 (ACPH_SHIFL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative acyl carrier protein phosphodiesterase
Short name=ACP phosphodiesterase
EC=3.1.4.14

Gene names

Name:	acpH
Ordered Locus Names:	SF0341, S0349

Organism

Shigella flexneri [Complete proteome] [HAMAP]

Taxonomic identifier

623 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	143 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950
Catalytic activity	Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950
Sequence similarities	Belongs to the AcpH family.
Caution	Could be the product of a pseudogene. The N-terminus is shorter than in related proteins.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	[acyl-carrier-protein] phosphodiesterase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 143	143	Putative acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950		PRO_0000226276

Sequences

	Sequence		Length	Mass (Da)
	Q83SG7 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A0731A290EB3F83D	FASTA	143	17,418
	10 20 30 40 50 60 MTDNLPEVRE AQEWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM 70 80 90 100 110 120 TILPDSPPRF INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLDAHY 130 140 DALETRFWQF YPRMMAQASH KAL

References

[1]

"Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157." Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y. , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J. Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 301 / Serotype 2a.

[2]

"Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T." Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R. Infect. Immun. 71:2775-2786(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700930 / 2457T / Serotype 2a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005674 Genomic DNA. Translation: AAN41999.1. AE014073 Genomic DNA. No translation available.
RefSeq	NP_706292.1. NC_004337.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	198214.SF0341.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN41999; AAN41999; SF0341.
GeneID	1027645.
KEGG	sfl:SF0341.
PATRIC	18712285. VBIShiFle86970_0391.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3124.
HOGENOM	HOG000275880.
KO	K08682.
OMA	RIRFANS.
ProtClustDB	CLSK384313.
Family and domain databases
HAMAP	MF_01950. AcpH. Divergent sequence.
InterPro	IPR007431. ACP_phosphodiesterase. [Graphical view]
Pfam	PF04336. DUF479. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACPH_SHIFL

Accession

Primary (citable) accession number: Q83SG7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 7, 2006
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program