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Protein

Glutaminase 2

Gene

glsA2

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei161SubstrateUniRule annotation1
Binding sitei168SubstrateUniRule annotation1
Binding sitei192SubstrateUniRule annotation1
Binding sitei244SubstrateUniRule annotation1
Binding sitei262Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 2UniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsA2UniRule annotation
Ordered Locus Names:SF1569, S1696
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001106251 – 308Glutaminase 2Add BLAST308

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ83RE2
SMRiQ83RE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiEPSGNPF

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

Q83RE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAMDNAIL ENILRQVRPL IGQGKVADYI PALATVDGSR LGIAICTVDG
60 70 80 90 100
QLFQAGDAQE RFSIQSISKV LSLVVAMRHY SEEEIWQRVG KDPSGSPFNS
110 120 130 140 150
LVQLEMEQGI PRNPFINTGA LVVCDMLQGR LSAPRQRMLE VVRGLSGVSD
160 170 180 190 200
ISYDTVVARS EFEHSARNAA IAWLMKSFGN FHHDVTTVLQ NYFHYCALKM
210 220 230 240 250
SCVELARTFV FLANQGKAIH IDEPVVTPMQ ARQINALMAT SGMYQNAGEF
260 270 280 290 300
AWRVGLPAKS GVGGGIVAIV PHEMAIAVWS PELDDAGNSL AGIAVLEQLT

KQLGRSVY
Length:308
Mass (Da):33,546
Last modified:June 1, 2003 - v1
Checksum:iD1A290F0B0C4DF34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN43157.1
AE014073 Genomic DNA Translation: AAP17051.1
RefSeqiNP_707450.1, NC_004337.2
WP_000257419.1, NZ_MTPK01000098.1

Genome annotation databases

EnsemblBacteriaiAAN43157; AAN43157; SF1569
AAP17051; AAP17051; S1696
GeneIDi1024764
KEGGisfl:SF1569
sfx:S1696
PATRICifig|198214.7.peg.1855

Similar proteinsi

Entry informationi

Entry nameiGLSA2_SHIFL
AccessioniPrimary (citable) accession number: Q83RE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health