Q83RB4 (Q83RB4_SHIFL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393

Gene names

Name:	sodC EMBL AAN43254.2
Ordered Locus Names:	S1805 EMBL AAP17140.1, SF1673 EMBL AAN43254.2

Organism

Shigella flexneri [Complete proteome] [HAMAP]

Taxonomic identifier

623 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q83RB4 [UniParc]. Last modified July 5, 2005. Version 4. Checksum: DC43B64712E8FA65	FASTA	178	18,168
	10 20 30 40 50 60 MNGGPMKRFS LAILALVVAT GAQAASEKVE MNLVTSQGVG QSIGSVTITE TDKGLEFSPD 70 80 90 100 110 120 LKALPPGEHG FHIHAKGSCQ PATKDGKASA AESAGGHLDP QNTGKHEGPE GTGHLGDLPA 130 140 150 160 170 LVVNNDGKAT DAVIAPRLKS LDEIKDKALM VHVGGDNMSD QPKPLGGGGE RYACGVIK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157." Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y. , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J. Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 301 EMBL AAN43254.2 and 301 / Serotype 2a.
[2]	"Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T." Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R. Infect. Immun. 71:2775-2786(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2457T EMBL AAP17140.1 and ATCC 700930 / 2457T / Serotype 2a.
[3]	Jin Q., Shen Y., Wang J.H., Liu H., Yang J., Yang F., Zhang X.B., Zhang J.Y., Yang G.W., Wu H.T., Dong J., Sun L.L., Xue Y., Zhao A.L., Gao Y.S., Zhu J.P., Chen S.X., Yao Z.J. , Wang Y., Lu W.C., Qiang B.Q., Wen Y.M., Hou Y.D. Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 301 EMBL AAN43254.2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005674 Genomic DNA. Translation: AAN43254.2. AE014073 Genomic DNA. Translation: AAP17140.1.
RefSeq	NP_707547.2. NC_004337.2. NP_837333.1. NC_004741.1.
3D structure databases
HSSP	HSSP built from PDB template 1ESO based on UniProtKB P53635.
SMR	Q83RB4. Positions 25-178.
ModBase	Search...
Protein-protein interaction databases
STRING	198214.SF1673.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN43254; AAN43254; SF1673. AAP17140; AAP17140; S1805.
GeneID	1024862. 1079362.
KEGG	sfl:SF1673. sfx:S1805.
PATRIC	18704998. VBIShiFle31049_1997.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000263449.
KO	K04565.
ProtClustDB	PRK10290.
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q83RB4_SHIFL

Accession

Primary (citable) accession number: Q83RB4
Secondary accession number(s): Q7UCE0

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 81 of the entry and version 4 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)