Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Superoxide dismutase (Cu-Zn)

Gene

sodC

Organism
Shigella flexneri
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Superoxide dismutase (Cu-Zn)Imported
Gene namesi
Name:sodCImported
Ordered Locus Names:S1805Imported, SF1673Imported
OrganismiShigella flexneriImported
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
ProteomesiUP000002673 Componenti: Chromosome UP000001006 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198214.SF1673.

Structurei

3D structure databases

ProteinModelPortaliQ83RB4.
SMRiQ83RB4. Positions 25-178.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000263449.
KOiK04565.
OMAiGARYACG.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83RB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGGPMKRFS LAILALVVAT GAQAASEKVE MNLVTSQGVG QSIGSVTITE
60 70 80 90 100
TDKGLEFSPD LKALPPGEHG FHIHAKGSCQ PATKDGKASA AESAGGHLDP
110 120 130 140 150
QNTGKHEGPE GTGHLGDLPA LVVNNDGKAT DAVIAPRLKS LDEIKDKALM
160 170
VHVGGDNMSD QPKPLGGGGE RYACGVIK
Length:178
Mass (Da):18,168
Last modified:July 5, 2005 - v4
Checksum:iDC43B64712E8FA65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN43254.2.
AE014073 Genomic DNA. Translation: AAP17140.1.
RefSeqiNP_707547.2. NC_004337.2.
NP_837333.1. NC_004741.1.

Genome annotation databases

EnsemblBacteriaiAAN43254; AAN43254; SF1673.
AAP17140; AAP17140; S1805.
GeneIDi1024862.
1079362.
KEGGisfl:SF1673.
sfx:S1805.
PATRICi18704998. VBIShiFle31049_1997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN43254.2.
AE014073 Genomic DNA. Translation: AAP17140.1.
RefSeqiNP_707547.2. NC_004337.2.
NP_837333.1. NC_004741.1.

3D structure databases

ProteinModelPortaliQ83RB4.
SMRiQ83RB4. Positions 25-178.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198214.SF1673.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN43254; AAN43254; SF1673.
AAP17140; AAP17140; S1805.
GeneIDi1024862.
1079362.
KEGGisfl:SF1673.
sfx:S1805.
PATRICi18704998. VBIShiFle31049_1997.

Phylogenomic databases

HOGENOMiHOG000263449.
KOiK04565.
OMAiGARYACG.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157."
    Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y.
    , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.
    Nucleic Acids Res. 30:4432-4441(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 301Imported and 301 / Serotype 2aImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2457TImported and ATCC 700930 / 2457T / Serotype 2aImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 301Imported.

Entry informationi

Entry nameiQ83RB4_SHIFL
AccessioniPrimary (citable) accession number: Q83RB4
Secondary accession number(s): Q7UCE0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: July 5, 2005
Last modified: April 1, 2015
This is version 96 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.