Q83PV4 (GLGA_SHIFL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	SF3452, S4311

Organism

Shigella flexneri [Complete proteome] [HAMAP]

Taxonomic identifier

623 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 477	477	Glycogen synthase HAMAP-Rule MF_00484		PRO_0000188645
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q83PV4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: C9B18973AD08414E	FASTA	477	52,781
	10 20 30 40 50 60 MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDARVL LPAFPDIRRG VTDAQVVSRR 70 80 90 100 110 120 DTFAGHITLL FGHYNGVGIY LIDAPHLYDR PGSPYHDTNL FAYTDNVLRF ALLGWVGAEM 130 140 150 160 170 180 ASGLDPFWRP DVVHVHDWHA GLAPAYLAAR GRPAKSVFTV HNLAYQGMFY AHHMNDIQLP 190 200 210 220 230 240 WSFFNIHGLE FNGQISFLKA GLYYADHITA VSPTYAREIT EPQFAYGMEG LLQQRHREGR 250 260 270 280 290 300 LSGVLNGVDE KIWSPETDLL LASRYTRDTL EDKAENKSQL QIAMGLKVDD KVPLFAVVSR 310 320 330 340 350 360 LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEYPGQVG VQIGYHEAFS 370 380 390 400 410 420 HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG LADTVSDCSL ENLADGVASG 430 440 450 460 470 FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF VQRQAMAMDF SWQVAAKSYR ELYYRLK

References

[1]

"Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157." Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y. , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J. Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 301 / Serotype 2a.

[2]

"Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T." Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R. Infect. Immun. 71:2775-2786(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700930 / 2457T / Serotype 2a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005674 Genomic DNA. Translation: AAN44912.1. AE014073 Genomic DNA. Translation: AAP19269.1.
RefSeq	NP_709205.1. NC_004337.2. NP_839458.1. NC_004741.1.
3D structure databases
ProteinModelPortal	Q83PV4.
ModBase	Search...
Protein-protein interaction databases
STRING	198214.SF3452.
Proteomic databases
PaxDb	Q83PV4.
PRIDE	Q83PV4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN44912; AAN44912; SF3452. AAP19269; AAP19269; S4311.
GeneID	1026461. 1080517.
KEGG	sfl:SF3452. sfx:S4311.
PATRIC	18710614. VBIShiFle31049_4711.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HOG000294941.
KO	K00703.
OMA	ADVIMVP.
ProtClustDB	PRK00654.
Enzyme and pathway databases
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_SHIFL

Accession

Primary (citable) accession number: Q83PV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program