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Protein

Elongation factor Ts

Gene

tsf

Organism
Tropheryma whipplei (strain TW08/27) (Whipple's bacillus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TsUniRule annotation
Short name:
EF-TsUniRule annotation
Gene namesi
Name:tsfUniRule annotation
Ordered Locus Names:TW319
OrganismiTropheryma whipplei (strain TW08/27) (Whipple's bacillus)
Taxonomic identifieri218496 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesTropheryma

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001612261 – 273Elongation factor TsAdd BLAST273

Structurei

3D structure databases

ProteinModelPortaliQ83NN3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni80 – 83Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation4

Sequence similaritiesi

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.
OrthoDBiPOG091H02HG.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83NN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDISMADVR LLRERLGVGV MDSRNALIEA GGDIERAVEI LRLKGLKSAE
60 70 80 90 100
KREGRSVSEG LVVSRQFATH AVLAELCCET DFVAKSDRFL ALSERVADLV
110 120 130 140 150
SDADSLETAL RVRCDEGSVA DLIALEAAVL GENVALRRFA RVEGSRFSVY
160 170 180 190 200
MHRTSSDLPP QVGVILAYEG HDDATARFIA QHIAFAAPEY LSVGDIPQGI
210 220 230 240 250
LQRERDLLTE ISRGEGKPEE VLPQIVEGRL VKLYKQNVLL EQDYVRDNKV
260 270
TISKVLEATG LRVISFARFR VGT
Length:273
Mass (Da):30,093
Last modified:June 1, 2003 - v1
Checksum:i2A83FCB1432E432C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX251411 Genomic DNA. Translation: CAD66992.1.
RefSeqiWP_011096272.1. NC_004551.1.

Genome annotation databases

EnsemblBacteriaiCAD66992; CAD66992; TW319.
KEGGitws:TW319.
PATRICi23999095. VBITroWhi42739_0383.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX251411 Genomic DNA. Translation: CAD66992.1.
RefSeqiWP_011096272.1. NC_004551.1.

3D structure databases

ProteinModelPortaliQ83NN3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD66992; CAD66992; TW319.
KEGGitws:TW319.
PATRICi23999095. VBITroWhi42739_0383.

Phylogenomic databases

HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.
OrthoDBiPOG091H02HG.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTS_TROW8
AccessioniPrimary (citable) accession number: Q83NN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.