Q83NF6 (SSRP_TROW8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	TW571

Organism

Tropheryma whipplei (strain TW08/27) (Whipple's bacillus) [Complete proteome] [HAMAP]

Taxonomic identifier

218496 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP MF_00023
Subcellular location	Cytoplasm Potential HAMAP MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	SsrA-binding protein HAMAP MF_00023		PRO_0000103060

Sequences

	Sequence		Length	Mass (Da)
	Q83NF6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A5871AFE3BA34E2C	FASTA	211	24,747
	10 20 30 40 50 60 MHRRSSKSYS SRNSKTPERS KIPDCVIASN KSAEYNYFLD KTFEAGLVLL GSEVKSVRQQ 70 80 90 100 110 120 KISLSEAYIY EDNSEIWLAN LYIPEHKTGG WTNHNPRRLR KLLLHKYQIA RLRKDLLIPG 130 140 150 160 170 180 ITLVPIKFYF RNGRAKLLIS LARGKKLIDK REVIKEREAT LEANRALKHR LRRPRAQRNT 190 200 210 QRSVTPRSTR ENKNVQRNKA RSARCNVRHE N

References

[1]

"Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei." Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L.G., Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., Relman D.A. Lancet 361:637-644(2003) [PubMed: 12606174] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW08/27.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX251412 Genomic DNA. Translation: CAD67237.1.
RefSeq	NP_789499.1. NC_004551.1.
3D structure databases
ProteinModelPortal	Q83NF6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q83NF6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1064775.
GenomeReviews	Gene locus TW571 in contig BX072543_GR.
KEGG	tws:TW571.
PATRIC	23999683. VBITroWhi42739_0661.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0691.
HOGENOM	HBG293422.
OMA	EKYEAGI.
PhylomeDB	Q83NF6.
ProtClustDB	PRK05422.
Enzyme and pathway databases
BioCyc	TWHI218496:TW0544-MONOMER.
Family and domain databases
HAMAP	MF_00023. SmpB. [Tree]
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Gene3D	G3DSA:2.40.280.10. SmpB. 1 hit.
KO	K03664.
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. SmpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_TROW8

Accession

Primary (citable) accession number: Q83NF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program