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Q83N94 (Q83N94_TROW8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3,4-dihydroxy-2-butanone 4-phosphate synthase RuleBase RU003843
Gene names
Name:ribB EMBL CAD67367.1
Ordered Locus Names:TW708
OrganismTropheryma whipplei (strain TW08/27) (Whipple's bacillus) [Complete proteome] [HAMAP]
Taxonomic identifier218496 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate By similarity. SAAS SAAS000422

Catalytic activity

D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate. SAAS SAAS000422

Cofactor

Binds 2 divalent metal cations per subunit. Magnesium or manganese By similarity. SAAS SAAS000422

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1. RuleBase RU003843 SAAS SAAS000422

Subunit structure

Homodimer By similarity. SAAS SAAS000422

Sequence similarities

Belongs to the DHBP synthase family. RuleBase RU003843

Sequences

Sequence LengthMass (Da)Tools
Q83N94 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: DA2B8DCC048176B9

FASTA21523,847
        10         20         30         40         50         60 
MRHIPDALNA LRAGRPVVVL DDKNRENEAD VIMAAQFATQ EWVAWIIRHT SGFLCVPLSN 

        70         80         90        100        110        120 
QRADKLQLPS MVAANEDRFK TAYTISVDAA DAAITTGISA ADRSLTIRTL AARDSSAKHL 

       130        140        150        160        170        180 
VRPGHILPLR ARDGGLLERR GHTEAAIELM RQAQLEPVAV IAELVSDTGE LLRGRALDEF 

       190        200        210 
IRKNNLVLVE ISQIIEYMKM SDLKDISMNL NRDCL

« Hide

References

[1]"Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei."
Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L.G., Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., Relman D.A.
Lancet 361:637-644(2003) [PubMed: 12606174] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX251412 Genomic DNA. Translation: CAD67367.1.
RefSeqNP_789629.1. NC_004551.1.

3D structure databases

HSSPHSSP built from PDB template 1K49 based on UniProtKB Q8TG90.
ProteinModelPortalQ83N94.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ83N94.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1064908.
GenomeReviewsGene locus TW708 in contig BX072543_GR.
KEGGtws:TW708.
PATRIC24000099. VBITroWhi42739_0859.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0108.
HOGENOMHBG735778.
OMAGDMIFAA.
PhylomeDBQ83N94.
ProtClustDBCLSK230228.

Enzyme and pathway databases

BioCycTWHI218496:TW0674-MONOMER.

Family and domain databases

InterProIPR017945. DHBP_synth_RibB-like_a/b_dom.
IPR000422. DHBP_synthase_RibB.
[Graphical view]
Gene3DG3DSA:3.90.870.10. DHBP_synth_RibB-like_a/b_dom. 1 hit.
KOK02858.
PfamPF00926. DHBP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55821. DHBP_synth_RibB-like_a/b_dom. 1 hit.
TIGRFAMsTIGR00506. RibB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ83N94_TROW8
AccessionPrimary (citable) accession number: Q83N94
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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