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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

goaG

Organism
Shigella flexneri
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Name:goaGImported
Ordered Locus Names:SF1307Imported
OrganismiShigella flexneriImported
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
ProteomesiUP000001006: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198214.SF1307.

Structurei

3D structure databases

ProteinModelPortaliQ83LB5.
SMRiQ83LB5. Positions 2-421.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83LB5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSNNEFHQRR LSATPRGVGV MCNFFAQSAE NATLKDVEGN EYIDFAAGIA
60 70 80 90 100
VLNTGHRHPD LVAAVEQQLQ QFTHTAYQIV PYESYVTLAE KINTLAPVSG
110 120 130 140 150
QAKTAFFTTG AEAVENAVKI ARAHTGRPSV IAFSGGFHGR TYMTMALTGK
160 170 180 190 200
VAPYKIGFGP FPGSVYHVPY PSDLHGISTQ DSLDAIERLF KSDIEAKQVA
210 220 230 240 250
AIIFEPVQGE CGFNVAPKEL VAAIRRLCDE HGIVMIADEV QSGFARTGKL
260 270 280 290 300
FAMDHYADKP DLMTMAKSLA GGMPLSGVVG NANIMDAPAP GGLGGTYAGN
310 320 330 340 350
PLAVAAAHAV LNIIDKESLC ERANQLGQRL KNTLIDAKES VPAIAAVRGL
360 370 380 390 400
GSMIAAEFND PQTGEPSAAI AQKIQQRALA QGLLLLTCGA YGNVIRFLYP
410 420
LTIPDAQFDA AMKILQDALS D
Length:421
Mass (Da):44,807
Last modified:June 1, 2003 - v1
Checksum:i2299E9DB7393923F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN42918.1.
RefSeqiNP_707211.1. NC_004337.2.

Genome annotation databases

EnsemblBacteriaiAAN42918; AAN42918; SF1307.
GeneIDi1024259.
KEGGisfl:SF1307.
PATRICi18714628. VBIShiFle86970_1533.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN42918.1.
RefSeqiNP_707211.1. NC_004337.2.

3D structure databases

ProteinModelPortaliQ83LB5.
SMRiQ83LB5. Positions 2-421.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198214.SF1307.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN42918; AAN42918; SF1307.
GeneIDi1024259.
KEGGisfl:SF1307.
PATRICi18714628. VBIShiFle86970_1533.

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157."
    Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y.
    , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.
    Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 301 / Serotype 2aImported.

Entry informationi

Entry nameiQ83LB5_SHIFL
AccessioniPrimary (citable) accession number: Q83LB5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 7, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.