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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi46ZincPROSITE-ProRule annotation1
Metal bindingi49ZincPROSITE-ProRule annotation1
Metal bindingi95ZincPROSITE-ProRule annotation1
Metal bindingi98ZincPROSITE-ProRule annotation1
Active sitei118NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Ordered Locus Names:SF1445, S1560
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001402941 – 137Peptide methionine sulfoxide reductase MsrBAdd BLAST137

Structurei

3D structure databases

ProteinModelPortaliQ83L66
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 129MsrBPROSITE-ProRule annotationAdd BLAST123

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X Bacteria
COG0229 LUCA
HOGENOMiHOG000243425
KOiK07305
OMAiYKASHKF

Family and domain databases

HAMAPiMF_01400 MsrB, 1 hit
InterProiView protein in InterPro
IPR028427 Met_Sox_Rdtase
IPR002579 Met_Sox_Rdtase_MsrB
IPR011057 Mss4-like_sf
PANTHERiPTHR10173 PTHR10173, 1 hit
PfamiView protein in Pfam
PF01641 SelR, 1 hit
SUPFAMiSSF51316 SSF51316, 1 hit
TIGRFAMsiTIGR00357 TIGR00357, 1 hit
PROSITEiView protein in PROSITE
PS51790 MSRB, 1 hit

Sequencei

Sequence statusi: Complete.

Q83L66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKPSAEEL KKNLSEMQFY VTQNHGTEPP FTGRLLHNKR DGVYHCLICD
60 70 80 90 100
APLFHSETKY DSGCGWPSFY EPVSEESIRY IKDLSHGMQR IEIRCGNCDA
110 120 130
HLGHVFPDGP QPTGERYCVN SASLRFTDGE NGEEING
Length:137
Mass (Da):15,452
Last modified:June 1, 2003 - v1
Checksum:i615B62E77EA4CF71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN43043.1
AE014073 Genomic DNA Translation: AAP16938.1
RefSeqiNP_707336.1, NC_004337.2
WP_001284613.1, NZ_NIYV01000062.1

Genome annotation databases

EnsemblBacteriaiAAN43043; AAN43043; SF1445
AAP16938; AAP16938; S1560
GeneIDi1024628
KEGGisfl:SF1445
sfx:S1560
PATRICifig|198214.7.peg.1701

Similar proteinsi

Entry informationi

Entry nameiMSRB_SHIFL
AccessioniPrimary (citable) accession number: Q83L66
Secondary accession number(s): Q7C1P9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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