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Protein

Glucokinase

Gene

glk

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 13ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:SF2454, S2593
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002151391 – 321GlucokinaseAdd BLAST321

Structurei

3D structure databases

ProteinModelPortaliQ83K86
SMRiQ83K86
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CHC Bacteria
COG0837 LUCA
HOGENOMiHOG000274469
KOiK00845
OMAiFCVLMGR

Family and domain databases

HAMAPiMF_00524 Glucokinase, 1 hit
InterProiView protein in InterPro
IPR003836 Glucokinase
PfamiView protein in Pfam
PF02685 Glucokinase, 1 hit
TIGRFAMsiTIGR00749 glk, 1 hit

Sequencei

Sequence statusi: Complete.

Q83K86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVIRVYLE
60 70 80 90 100
EHKVEVKDGC IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND
110 120 130 140 150
FTAVSMAIPM LKKEHLIQFG GAEPVEGKPI AVYGAGTGLG VAHLVHVDKR
160 170 180 190 200
WVSLPGEGGH VDFAPNSEEE AIILEILRAE IGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVKADNRLP ENLKPKDITE RALADSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
NLGTFGGVFI AGGIVPRFLE FFKASGFRAA FEDKGRFKEY VHDIPVYLIV
310 320
HDYPGLLGSG AHLRQTLGHI L
Length:321
Mass (Da):34,772
Last modified:June 1, 2003 - v1
Checksum:i2D6CC1E1341A3823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN43962.1
AE014073 Genomic DNA Translation: AAP17773.1
RefSeqiNP_708255.1, NC_004337.2
WP_000170347.1, NZ_MTPK01000001.1

Genome annotation databases

EnsemblBacteriaiAAN43962; AAN43962; SF2454
AAP17773; AAP17773; S2593
GeneIDi1025571
KEGGisfl:SF2454
sfx:S2593
PATRICifig|198214.7.peg.2932

Similar proteinsi

Entry informationi

Entry nameiGLK_SHIFL
AccessioniPrimary (citable) accession number: Q83K86
Secondary accession number(s): Q7C0L2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health