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Q83K86 (GLK_SHIFL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:SF2454, S2593
OrganismShigella flexneri [Complete proteome] [HAMAP]
Taxonomic identifier623 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524

Subcellular location

Cytoplasm By similarity HAMAP MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glucokinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 321321Glucokinase HAMAP MF_00524
PRO_0000215139

Regions

Nucleotide binding8 – 136ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q83K86 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 2D6CC1E1341A3823

FASTA32134,772
        10         20         30         40         50         60 
MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVIRVYLE EHKVEVKDGC 

        70         80         90        100        110        120 
IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND FTAVSMAIPM LKKEHLIQFG 

       130        140        150        160        170        180 
GAEPVEGKPI AVYGAGTGLG VAHLVHVDKR WVSLPGEGGH VDFAPNSEEE AIILEILRAE 

       190        200        210        220        230        240 
IGHVSAERVL SGPGLVNLYR AIVKADNRLP ENLKPKDITE RALADSCTDC RRALSLFCVI 

       250        260        270        280        290        300 
MGRFGGNLAL NLGTFGGVFI AGGIVPRFLE FFKASGFRAA FEDKGRFKEY VHDIPVYLIV 

       310        320 
HDYPGLLGSG AHLRQTLGHI L 

« Hide

References

[1]"Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157."
Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y. expand/collapse author list , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.
Nucleic Acids Res. 30:4432-4441(2002) [PubMed: 12384590] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 301 / Serotype 2a.
[2]"Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T."
Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.
Infect. Immun. 71:2775-2786(2003) [PubMed: 12704152] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700930 / 2457T / Serotype 2a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005674 Genomic DNA. Translation: AAN43962.1.
AE014073 Genomic DNA. Translation: AAP17773.1.
RefSeqNP_708255.1. NC_004337.2.
NP_837963.1. NC_004741.1.

3D structure databases

ProteinModelPortalQ83K86.
SMRQ83K86. Positions 2-321.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000088367; EBESCP00000085189; EBESCG00000087412.
EBESCT00000089523; EBESCP00000086159; EBESCG00000088567.
GeneID1025571.
1078864.
GenomeReviewsGene locus SF2454 in contig AE005674_GR.
Gene locus S2593 in contig AE014073_GR.
KEGGsfl:SF2454.
sfx:S2593.
PATRIC18706794. VBIShiFle31049_2871.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000011054.
HOGENOMHBG644410.
OMADITSHAL.
ProtClustDBPRK00292.

Enzyme and pathway databases

BioCycSFLE198214:AAN43962.1-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
[Tree]
InterProIPR003836. Glucokinase.
[Graphical view]
KOK00845.
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. Glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_SHIFL
AccessionPrimary (citable) accession number: Q83K86
Secondary accession number(s): Q7C0L2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families