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Q83K86

- GLK_SHIFL

UniProt

Q83K86 - GLK_SHIFL

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Protein
Glucokinase
Gene
glk, SF2454, S2593
Organism
Shigella flexneri
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:SF2454, S2593
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
ProteomesiUP000001006: Chromosome, UP000002673: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlucokinaseUniRule annotation
PRO_0000215139Add
BLAST

Proteomic databases

PaxDbiQ83K86.

Interactioni

Protein-protein interaction databases

STRINGi198214.SF2454.

Structurei

3D structure databases

ProteinModelPortaliQ83K86.
SMRiQ83K86. Positions 2-321.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDWVEMTN.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83K86-1 [UniParc]FASTAAdd to Basket

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MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVIRVYLE    50
EHKVEVKDGC IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND 100
FTAVSMAIPM LKKEHLIQFG GAEPVEGKPI AVYGAGTGLG VAHLVHVDKR 150
WVSLPGEGGH VDFAPNSEEE AIILEILRAE IGHVSAERVL SGPGLVNLYR 200
AIVKADNRLP ENLKPKDITE RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
NLGTFGGVFI AGGIVPRFLE FFKASGFRAA FEDKGRFKEY VHDIPVYLIV 300
HDYPGLLGSG AHLRQTLGHI L 321
Length:321
Mass (Da):34,772
Last modified:June 1, 2003 - v1
Checksum:i2D6CC1E1341A3823
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005674 Genomic DNA. Translation: AAN43962.1.
AE014073 Genomic DNA. Translation: AAP17773.1.
RefSeqiNP_708255.1. NC_004337.2.
NP_837963.1. NC_004741.1.

Genome annotation databases

EnsemblBacteriaiAAN43962; AAN43962; SF2454.
AAP17773; AAP17773; S2593.
GeneIDi1025571.
1078864.
KEGGisfl:SF2454.
sfx:S2593.
PATRICi18706794. VBIShiFle31049_2871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005674 Genomic DNA. Translation: AAN43962.1 .
AE014073 Genomic DNA. Translation: AAP17773.1 .
RefSeqi NP_708255.1. NC_004337.2.
NP_837963.1. NC_004741.1.

3D structure databases

ProteinModelPortali Q83K86.
SMRi Q83K86. Positions 2-321.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198214.SF2454.

Proteomic databases

PaxDbi Q83K86.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN43962 ; AAN43962 ; SF2454 .
AAP17773 ; AAP17773 ; S2593 .
GeneIDi 1025571.
1078864.
KEGGi sfl:SF2454.
sfx:S2593.
PATRICi 18706794. VBIShiFle31049_2871.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi DWVEMTN.
OrthoDBi EOG64BQ47.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157."
    Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L., Xue Y.
    , Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.
    Nucleic Acids Res. 30:4432-4441(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 301 / Serotype 2a.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700930 / 2457T / Serotype 2a.

Entry informationi

Entry nameiGLK_SHIFL
AccessioniPrimary (citable) accession number: Q83K86
Secondary accession number(s): Q7C0L2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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