SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q83HP8

- PGK_TROW8

UniProt

Q83HP8 - PGK_TROW8

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoglycerate kinase
Gene
pgk, TW471
Organism
Tropheryma whipplei (strain TW08/27) (Whipple's bacillus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei157 – 1571Substrate By similarity
Binding sitei208 – 2081ATP By similarity
Binding sitei296 – 2961ATP; via carbonyl oxygen By similarity
Binding sitei327 – 3271ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3564ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:TW471
OrganismiTropheryma whipplei (strain TW08/27) (Whipple's bacillus)
Taxonomic identifieri218496 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeTropheryma
ProteomesiUP000001413: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395Phosphoglycerate kinaseUniRule annotation
PRO_0000146031Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi218496.TW471.

Structurei

3D structure databases

ProteinModelPortaliQ83HP8.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 223Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83HP8-1 [UniParc]FASTAAdd to Basket

« Hide

MRTLGGFTFP CDAPVFVRVD FNVPMDEVGT ITDDLRIRAS LPTIESLLGR    50
GAPLILISHL GRPVKNEQQG FSLKPCAERL SEYIGVNVPL VDFLDLDTKL 100
YGELTRHLDK SGIVLFENIR FFAEETSKAQ ADRRILAEQL APFAGAYVND 150
AFGASHRRHA SVYELAQAFS NKAAGFLIES EMQAFSHLAS EAKRPYTVIL 200
GGAKLSDKLR LIENILPTVD RLLLCGGMAF TFLAAQGCET GKSLLEESFI 250
SEANKIIDFA KQNNVELILP VDVIEARSLT SPLGVVSKAE SISYMGLDIG 300
PETQSIFRNV IQDSKTVFWN GPAGLFENPS FSNGTRALLD ALSSSSAFTF 350
IGGGDTAAAV SLLGFDYGDF SHVSTGGGAC LELLEGKILP ALEVL 395
Length:395
Mass (Da):42,679
Last modified:June 1, 2003 - v1
Checksum:iFE3D38502096E016
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX251411 Genomic DNA. Translation: CAD67138.1.
RefSeqiNP_789400.1. NC_004551.1.

Genome annotation databases

EnsemblBacteriaiCAD67138; CAD67138; TW471.
GeneIDi1064311.
KEGGitws:TW471.
PATRICi23999427. VBITroWhi42739_0539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX251411 Genomic DNA. Translation: CAD67138.1 .
RefSeqi NP_789400.1. NC_004551.1.

3D structure databases

ProteinModelPortali Q83HP8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 218496.TW471.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD67138 ; CAD67138 ; TW471 .
GeneIDi 1064311.
KEGGi tws:TW471.
PATRICi 23999427. VBITroWhi42739_0539.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW08/27.

Entry informationi

Entry nameiPGK_TROW8
AccessioniPrimary (citable) accession number: Q83HP8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi