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Q83HM0 (Q83HM0_TROW8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653
Gene names
Name:map EMBL CAD67178.1
Ordered Locus Names:TW511
OrganismTropheryma whipplei (strain TW08/27) (Whipple's bacillus) [Complete proteome] [HAMAP]
Taxonomic identifier218496 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653

Catalytic activity

Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653

Cofactor

Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653

Sequence similarities

Belongs to the peptidase M24A family. RuleBase RU003653

Sequences

Sequence LengthMass (Da)Tools
Q83HM0 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 6ACAECB00C784FC1

FASTA28932,058
        10         20         30         40         50         60 
MTPKNAYGHL VPGDISAARW VDPKIARPNY VGKKRVPRYT GSDIYNKDEI ERVRAAGSIA 

        70         80         90        100        110        120 
SQTLDYLAEH IRAGITTDEL DRLAHEFITS KGAYPSPLGY QGFPKSICTS INEVICHGIP 

       130        140        150        160        170        180 
DNTVLEDCDI VNVDVTAFFE GMHGDTNRTF IIGNAPEATK NLVKNTEEAL HVAIKAVAPG 

       190        200        210        220        230        240 
RRVNVIGLTI ERLAKRFNYG VVREFTGHGV GRAFHTGLVI PHYDATPYYD RILKPGMIFT 

       250        260        270        280 
IEPMLNLGTR HWNMWEDGWT AVTKDLLPSA QFEHTIVVTQ NGAEILTLS

« Hide

References

[1]"Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei."
Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L.G., Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., Relman D.A.
Lancet 361:637-644(2003) [PubMed: 12606174] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX251411 Genomic DNA. Translation: CAD67178.1.
RefSeqNP_789440.1. NC_004551.1.

3D structure databases

HSSPHSSP built from PDB template 1MAT based on UniProtKB P07906.
ProteinModelPortalQ83HM0.
SMRQ83HM0. Positions 9-288.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ83HM0.

Protein family/group databases

MEROPSM24.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1064715.
GenomeReviewsGene locus TW511 in contig BX072543_GR.
KEGGtws:TW511.
PATRIC23999519. VBITroWhi42739_0582.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0024.
HOGENOMHBG299384.
OMAENGCEIM.
PhylomeDBQ83HM0.
ProtClustDBPRK05716.

Enzyme and pathway databases

BioCycTWHI218496:TW0485-MONOMER.

Family and domain databases

InterProIPR001714. Pept_M24_MAP.
IPR000994. Pept_M24_structural-domain.
IPR002467. Pept_M24A_MAP1.
[Graphical view]
Gene3DG3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KOK01265.
PfamPF00557. Peptidase_M24. 1 hit.
[Graphical view]
PRINTSPR00599. MAPEPTIDASE.
SUPFAMSSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMsTIGR00500. Met_pdase_I. 1 hit.
PROSITEPS00680. MAP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ83HM0_TROW8
AccessionPrimary (citable) accession number: Q83HM0
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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