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Protein
Submitted name:

Pyruvate dehydrogenase E1 component, alpha subunit

Gene

pdhA

Organism
Tropheryma whipplei (strain TW08/27) (Whipple's bacillus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

PyruvateImported

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E1 component, alpha subunitImported (EC:1.2.4.4Imported)
Gene namesi
Name:pdhAImported
Ordered Locus Names:TW799Imported
OrganismiTropheryma whipplei (strain TW08/27) (Whipple's bacillus)Imported
Taxonomic identifieri218496 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeTropheryma
ProteomesiUP000001413 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi218496.TW799.

Structurei

3D structure databases

ProteinModelPortaliQ83H69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1071.
HOGENOMiHOG000281335.
KOiK00161.
OMAiWKLKDPI.
OrthoDBiEOG6VMTKR.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR017596. PdhA/BkdA.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
TIGRFAMsiTIGR03181. PDH_E1_alph_x. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83H69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDKGYPVVQ FLRPDGSFCP SETAEPFLSH AQSLDVEDIQ RFYRDIILVR
60 70 80 90 100
QIDHEAALLQ RRGELALWPP VYGQEASQIG ATYACSENDM IFPSYRDHAV
110 120 130 140 150
MHARGIDLVH IAKLFRGASN NDWDVRQHKV WGYTLCIGAQ VLHSTGYAIG
160 170 180 190 200
IVLERQMSCT DDNSGYPEAV MVWFGDGASS QGDVSESMVF AARYQTPQVF
210 220 230 240 250
MLQNNQYAIS VPASVPSAAC PLYKRGYGFG IPGIRIDGND VIAAYAVVRE
260 270 280 290 300
YMDRARSGKG PHLIEAFTYR LGAHTTSDDP TRYRSEDEHR EWLALDPIIR
310 320 330 340 350
LERYLFSLGV EKTWFDRIRA DIQLSVIGFR NAVLSIPQPD TKKIFDNVYS
360 370
AYHPLVSSQS AHLLGLTESR
Length:370
Mass (Da):41,650
Last modified:May 31, 2003 - v1
Checksum:i1610B402A194E0B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX251412 Genomic DNA. Translation: CAD67458.1.
RefSeqiNP_789720.1. NC_004551.1.

Genome annotation databases

EnsemblBacteriaiCAD67458; CAD67458; TW799.
KEGGitws:TW799.
PATRICi24000329. VBITroWhi42739_0964.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX251412 Genomic DNA. Translation: CAD67458.1.
RefSeqiNP_789720.1. NC_004551.1.

3D structure databases

ProteinModelPortaliQ83H69.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218496.TW799.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD67458; CAD67458; TW799.
KEGGitws:TW799.
PATRICi24000329. VBITroWhi42739_0964.

Phylogenomic databases

eggNOGiCOG1071.
HOGENOMiHOG000281335.
KOiK00161.
OMAiWKLKDPI.
OrthoDBiEOG6VMTKR.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR017596. PdhA/BkdA.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
TIGRFAMsiTIGR03181. PDH_E1_alph_x. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW08/27Imported.

Entry informationi

Entry nameiQ83H69_TROW8
AccessioniPrimary (citable) accession number: Q83H69
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2003
Last sequence update: May 31, 2003
Last modified: March 31, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.