Q83GK8 (Q83GK8_TROWT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Name:	map EMBL AAO44356.1
Ordered Locus Names:	TWT259
ORF Names:	TWT_259 EMBL AAO44356.1

Organism

Tropheryma whipplei (strain Twist) (Whipple's bacillus) [Complete proteome] [HAMAP]

Taxonomic identifier

203267 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL AAO44356.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q83GK8 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4AB071FF2504EB68	FASTA	308	34,241
	10 20 30 40 50 60 MAKRCSRGQF PSERPYSSIM TPKNAYGHLV PGDISAARWV DPKIARPNYV GKKRVPRYTG 70 80 90 100 110 120 SDIYNKDEIE RVRAAGSIAS QTLDYLAEHI RAGITTDELD RLAHEFITSK GAYPSPLGYQ 130 140 150 160 170 180 GFPKSICTSI NEVICHGIPD NTVLEDCDIV NVDVTAFFEG MHGDTNRTFI IGNAPEATKN 190 200 210 220 230 240 LVKNTEEALH VAIKAVAPGR RVNVIGLTIE RLAKRFNYGV VREFTGHGVG RAFHTGLVIP 250 260 270 280 290 300 HYDATPYYDR ILKPGMIFTI EPMLNLGTRH WNMWEDGWTA VTKDLLPSAQ FEHTIVVTQN GAEILTLS

References

[1]	"Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome." Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M., Claverie J.-M. Genome Res. 13:1800-1809(2003) [PubMed: 12902375] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014184 Genomic DNA. Translation: AAO44356.1.
RefSeq	NP_787387.2. NC_004572.3.
3D structure databases
HSSP	HSSP built from PDB template 1MAT based on UniProtKB P07906.
ProteinModelPortal	Q83GK8.
SMR	Q83GK8. Positions 28-307.
ModBase	Search...
Protein-protein interaction databases
STRING	Q83GK8.
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1089509.
GenomeReviews	Gene locus TWT259 in contig AE014184_GR.
KEGG	twh:TWT259.
PATRIC	23997011. VBITroWhi72342_0388.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0024.
HOGENOM	HBG299384.
OMA	ENGCEIM.
PhylomeDB	Q83GK8.
ProtClustDB	PRK05716.
Enzyme and pathway databases
BioCyc	TWHI203267:TW259-MONOMER.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
PROSITE	PS00680. MAP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q83GK8_TROWT

Accession

Primary (citable) accession number: Q83GK8

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)