Q83FV5 (GCP_TROWT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	TWT_591

Organism

Tropheryma whipplei (strain Twist) (Whipple's bacillus) [Complete proteome] [HAMAP]

Taxonomic identifier

203267 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 401	401	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303604

Sequences

	Sequence		Length	Mass (Da)
	Q83FV5 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 7D12DD242F64DB5D	FASTA	401	42,363
	10 20 30 40 50 60 MSIILGIETS CDETGVGIVS GSTVLANEVA SSSLRHKPFG GVIPEIAARA HLEYLPNLLE 70 80 90 100 110 120 LALETAQLCI KDIDGIAVTA GPGLVTSLSV GVSAAKALGL STGTPVYGVN HLVGHAVSAF 130 140 150 160 170 180 LDDYTNDGLG VIHRRDSIGS NGIENDASST HSHTHTTQVN RHSNLCVYTP PRRVLRDVCK 190 200 210 220 230 240 YMHVRDSVVL LASGGHSCLL KIHNNKISLL GETLDDAAGE AFDKIARLMG LQYPGGPAIE 250 260 270 280 290 300 MLASSGNPNA VEFPRALLTH FEEHNRYSFS FSGLKTAVGR VVERIKSNPA HSIPKIEDIA 310 320 330 340 350 360 ASFQEAVADV LTAKTVAAAL ASDVDLIVMG GGVAANNRIR EMLCERAKIH GLDVKIPPIA 370 380 390 400 LCTDNGAMIA AAGSWLMQLG YNPSHSRFSP VSIMPLTQMV V

References

[1]

"Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome." Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M., Claverie J.-M. Genome Res. 13:1800-1809(2003) [PubMed: 12902375] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Twist.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014184 Genomic DNA. Translation: AAO44688.1.
RefSeq	NP_787719.1. NC_004572.3.
3D structure databases
ProteinModelPortal	Q83FV5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q83FV5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1482576.
GenomeReviews	Gene locus TWT_591 in contig AE014184_GR.
KEGG	twh:TWT591.
PATRIC	23997757. VBITroWhi72342_0744.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q83FV5.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	TWHI203267:TW591-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 2 hits. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_TROWT

Accession

Primary (citable) accession number: Q83FV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program