Q83FR9 (Q83FR9_TROWT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Name:	gcvT EMBL AAO44735.1
Ordered Locus Names:	TWT638
ORF Names:	TWT_638 EMBL AAO44735.1

Organism

Tropheryma whipplei (strain Twist) (Whipple's bacillus) [Complete proteome] [HAMAP]

Taxonomic identifier

203267 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. SAAS SAAS006223 RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase SAAS SAAS006223 RuleBase RU003981 Methyltransferase EMBL AAO44735.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q83FR9 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: E5B4CE02F824DF03	FASTA	356	39,120
	10 20 30 40 50 60 MAMTRVSPLD NEHKALGAIF TCFAGYKLPV RYKSDIAEHT AVRQGCGIFD LSHMAEIFVS 70 80 90 100 110 120 GVNAGLELDI ALTGHFSDMT CGRAKYTLIL NEQGGIEDDL IVYRIDDKNY MVVANGINRK 130 140 150 160 170 180 KVFSLLRDRV HTSDIKDETD SISLVAVQGP ESESLIRDLF HESGNLRYFS HRCYPHGGTD 190 200 210 220 230 240 RSEKLSCSIV ARTGYTGEDG FEIFTPNDSV VSIWRALIER GATPCGLAAR NTLRIEAGMP 250 260 270 280 290 300 LYGHELRADL NPVQAGLERF ISPPCIGCDR INHSGDFPLL VGLSIDGRRA AREGYTIYSS 310 320 330 340 350 SNIPVGTVTS GCFSPTLGCS IAMAYVKAKA RSAQLYIDIR GSMTPCKVVP MPFYRR

References

[1]	"Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome." Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M., Claverie J.-M. Genome Res. 13:1800-1809(2003) [PubMed: 12902375] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014184 Genomic DNA. Translation: AAO44735.1.
RefSeq	NP_787766.1. NC_004572.3.
3D structure databases
ProteinModelPortal	Q83FR9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q83FR9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1482076.
GenomeReviews	Gene locus TWT638 in contig AE014184_GR.
KEGG	twh:TWT638.
PATRIC	23997917. VBITroWhi72342_0817.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	KALYGGM.
PhylomeDB	Q83FR9.
ProtClustDB	CLSK230190.
Enzyme and pathway databases
BioCyc	TWHI203267:TW638-MONOMER.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q83FR9_TROWT

Accession

Primary (citable) accession number: Q83FR9

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)