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Q83FM8 (Q83FM8_TROWT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3,4-dihydroxy-2-butanone 4-phosphate synthase RuleBase RU003843
Gene names
Ordered Locus Names:TWT689
ORF Names:TWT_689 EMBL AAO44786.1
OrganismTropheryma whipplei (strain Twist) (Whipple's bacillus) [Complete proteome] [HAMAP]
Taxonomic identifier203267 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate By similarity. SAAS SAAS000422

Catalytic activity

D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate. SAAS SAAS000422

Cofactor

Binds 2 divalent metal cations per subunit. Magnesium or manganese By similarity. SAAS SAAS000422

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1. RuleBase RU003843 SAAS SAAS000422

Subunit structure

Homodimer By similarity. SAAS SAAS000422

Sequence similarities

Belongs to the DHBP synthase family. RuleBase RU003843

Sequences

Sequence LengthMass (Da)Tools
Q83FM8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: DA2B8DCC048176B9

FASTA21523,847
        10         20         30         40         50         60 
MRHIPDALNA LRAGRPVVVL DDKNRENEAD VIMAAQFATQ EWVAWIIRHT SGFLCVPLSN 

        70         80         90        100        110        120 
QRADKLQLPS MVAANEDRFK TAYTISVDAA DAAITTGISA ADRSLTIRTL AARDSSAKHL 

       130        140        150        160        170        180 
VRPGHILPLR ARDGGLLERR GHTEAAIELM RQAQLEPVAV IAELVSDTGE LLRGRALDEF 

       190        200        210 
IRKNNLVLVE ISQIIEYMKM SDLKDISMNL NRDCL

« Hide

References

[1]"Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome."
Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M., Claverie J.-M.
Genome Res. 13:1800-1809(2003) [PubMed: 12902375] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014184 Genomic DNA. Translation: AAO44786.1.
RefSeqNP_787817.1. NC_004572.3.

3D structure databases

HSSPHSSP built from PDB template 1K49 based on UniProtKB Q8TG90.
ProteinModelPortalQ83FM8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ83FM8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1482128.
GenomeReviewsGene locus TWT689 in contig AE014184_GR.
KEGGtwh:TWT689.
PATRIC23998023. VBITroWhi72342_0869.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0108.
HOGENOMHBG735778.
OMAGDMIFAA.
ProtClustDBCLSK230228.

Enzyme and pathway databases

BioCycTWHI203267:TW689-MONOMER.

Family and domain databases

InterProIPR017945. DHBP_synth_RibB-like_a/b_dom.
IPR000422. DHBP_synthase_RibB.
[Graphical view]
Gene3DG3DSA:3.90.870.10. DHBP_synth_RibB-like_a/b_dom. 1 hit.
KOK02858.
PfamPF00926. DHBP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55821. DHBP_synth_RibB-like_a/b_dom. 1 hit.
TIGRFAMsTIGR00506. RibB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ83FM8_TROWT
AccessionPrimary (citable) accession number: Q83FM8
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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