Q83FD6 (RECF_COXBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	CBU_0003

Organism

Coxiella burnetii

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity. HAMAP MF_00365
Subcellular location	Cytoplasm By similarity HAMAP MF_00365.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW SOS response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW single-stranded DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 357	357	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000196412
Regions
	Nucleotide binding	31 – 38	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q83FD6 [UniParc]. Last modified December 16, 2008. Version 2. Checksum: 55560EBA41080DC7	FASTA	357	41,039
	10 20 30 40 50 60 MPYIGSLKVN QFRNLADVDI TPHSQFNFFF GQNGAGKTSI LESIYYLSVG RSFRTHLPQR 70 80 90 100 110 120 LIQDNTDRFL IFITLYNGTQ FIPLGVERDC HGDRCLRING ETASSWSLAA KRLPLCSLSA 130 140 150 160 170 180 MSHRFLLDGP RVRRQFLDWL MFHVEPSFFS IWQRLQRSLK QRNAALKAKL PLGEITHWDK 190 200 210 220 230 240 MLVEDGERLH QLRQNVVTEF KPLFTQMLQQ FLPAYPLIGH YFRGWSEKYS LMEQLQINLK 250 260 270 280 290 300 QDLQRGYTQA GPQRADFRLT LGDLPAQDIL SQGQQKLVTY ALHFAQGLLL KEKTGISPIY 310 320 330 340 350 LIDDLPAELD ANKRDCVIDL VNCLESQVFI SGIDPNEIRL PPHSTLFHVK HGKVAAL

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016828 Genomic DNA. Translation: AAO89573.2.
RefSeq	NP_819059.2. NC_002971.3.
3D structure databases
ProteinModelPortal	Q83FD6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1207923.
GenomeReviews	Gene locus CBU_0003 in contig AE016828_GR.
KEGG	cbu:CBU_0003.
NMPDR	fig|227377.1.peg.3.
PATRIC	17928683. VBICoxBur82552_0004.
TIGR	CBU_0003.
Phylogenomic databases
HOGENOM	HBG645124.
OMA	GQQRTLV.
ProtClustDB	CLSK913765.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0003-MONOMER.
Family and domain databases
HAMAP	MF_00365. RecF. [Tree]
InterPro	IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR003395. RecF/RecN/SMC. [Graphical view]
KO	K03629.
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00611. Recf. 1 hit.
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_COXBU

Accession

Primary (citable) accession number: Q83FD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
Last sequence update:	December 16, 2008
Last modified:	January 25, 2012
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program