Q83F44 (METN_COXBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Methionine import ATP-binding protein MetN
EC=3.6.3.-

Gene names

Name:	metN
Ordered Locus Names:	CBU_0107

Organism

Coxiella burnetii

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system By similarity. HAMAP MF_01719
Subunit structure	The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_01719.
Sequence similarities	Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Amino-acid transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	methionine transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW amino acid-transporting ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	Methionine import ATP-binding protein MetN HAMAP MF_01719		PRO_0000270290
Regions
	Domain	2 – 241	240	ABC transporter
	Nucleotide binding	38 – 45	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q83F44 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1A5FCA5805BA27C5	FASTA	351	39,354
	10 20 30 40 50 60 MIELRNVTKT YSAKQGGVLA LSDINLRVSA GEMFGVIGKS GAGKSTLIRC VNLLERPDKG 70 80 90 100 110 120 SVIVDGQVLT TLSSKVLRQA RHRMGMVFQH FNLLSARTAY QNIAFPLQLL GKNPTEIRKV 130 140 150 160 170 180 VLPLLELTDL TAKINAYPSQ LSGGQKQRVA IARALVTNPT VLLCDEMTSA LDPETTHSIL 190 200 210 220 230 240 QLLKNINREL NLSILLITHE MEVIKTVADR VAVLDQGRIV EENDVVSLFK RPKTEIAKKF 250 260 270 280 290 300 THSSIKVKLP EILRNRLQKT TLDEGYALLR IDFTEHTAET PIIDEFIRKF DLQVNILQAR 310 320 330 340 350 LEFLRDDSIG MMLVALRNVK DTLPQGIAYL NEKGLQVEVL GYVSADDWRY R

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016828 Genomic DNA. Translation: AAO89671.1.
RefSeq	NP_819157.1. NC_002971.3.
3D structure databases
HSSP	HSSP built from PDB template 1B0U based on UniProtKB P02915.
ProteinModelPortal	Q83F44.
SMR	Q83F44. Positions 1-343.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1207978.
GenomeReviews	Gene locus CBU_0107 in contig AE016828_GR.
KEGG	cbu:CBU_0107.
NMPDR	fig|227377.1.peg.101.
PATRIC	17928897. VBICoxBur82552_0109.
TIGR	CBU_0107.
Phylogenomic databases
HOGENOM	HBG758042.
OMA	KHGRYPA.
PhylomeDB	Q83F44.
ProtClustDB	CLSK913838.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0107-MONOMER.
Family and domain databases
HAMAP	MF_01719. ABC_ATPase_MetN. [Tree]
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017908. ABC_transprt_methionine_MetN_C. IPR003593. ATPase_AAA+_core. IPR018449. NIL_domain. [Graphical view]
KO	K02071.
Pfam	PF00005. ABC_tran. 1 hit. PF09383. NIL. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. SM00930. NIL. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51264. METN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

METN_COXBU

Accession

Primary (citable) accession number: Q83F44

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program