ID   MRAZ_COXBU              Reviewed;         152 AA.
AC   Q83F36;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008};
GN   OrderedLocusNames=CBU_0115;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO89679.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016828; AAO89679.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_819165.2; NC_002971.3.
DR   AlphaFoldDB; Q83F36; -.
DR   SMR; Q83F36; -.
DR   STRING; 227377.CBU_0115; -.
DR   EnsemblBacteria; AAO89679; AAO89679; CBU_0115.
DR   GeneID; 1207986; -.
DR   KEGG; cbu:CBU_0115; -.
DR   PATRIC; fig|227377.7.peg.118; -.
DR   eggNOG; COG2001; Bacteria.
DR   HOGENOM; CLU_107907_2_0_6; -.
DR   OrthoDB; 9807753at2; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:2000143; P:negative regulation of DNA-templated transcription initiation; IBA:GO_Central.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   Gene3D; 3.40.1550.20; Transcriptional regulator MraZ domain; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR038619; MraZ_sf.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR037914; SpoVT-AbrB_sf.
DR   NCBIfam; TIGR00242; division/cell wall cluster transcriptional repressor MraZ; 1.
DR   PANTHER; PTHR34701; TRANSCRIPTIONAL REGULATOR MRAZ; 1.
DR   PANTHER; PTHR34701:SF1; TRANSCRIPTIONAL REGULATOR MRAZ; 1.
DR   Pfam; PF02381; MraZ; 2.
DR   SUPFAM; SSF89447; AbrB/MazE/MraZ-like; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..152
FT                   /note="Transcriptional regulator MraZ"
FT                   /id="PRO_0000108475"
FT   DOMAIN          5..52
FT                   /note="SpoVT-AbrB 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT   DOMAIN          81..124
FT                   /note="SpoVT-AbrB 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ   SEQUENCE   152 AA;  17339 MW;  B4DDECD1A6A64B59 CRC64;
     MFRGLNPIAV DAKGRIAIPA RYREPIESEA DGILVVTIDT EERCLLIYTH PQWEQIEQKL
     ENLPSYHPAS RRIQRLLIGH ATEVELDRSG RILIPPVLRE YAGLGSMVML VGQGKKFELW
     GKSQWETARE DWLAEELPKG DDLPPELRSL SL
//