mraZ

Functionⁱ

GO - Molecular functionⁱ

transcription factor activity, sequence-specific DNA binding Source: GO_Central
transcription regulatory region sequence-specific DNA binding Source: GO_Central

GO - Biological processⁱ

negative regulation of DNA-templated transcription, initiation Source: GO_Central
transcription, DNA-templated Source: UniProtKB-KW

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Transcriptional regulator MraZ
Gene namesⁱ	Name:mraZUniRule annotation Ordered Locus Names:CBU_0115
Organismⁱ	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifierⁱ	227377 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella › Coxiella burnetii
Proteomesⁱ	UP000002671 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm › nucleoid
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01008

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-KW
nucleoid Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000108475	1 – 152	Transcriptional regulator MraZAdd BLAST		152

Proteomic databases

PRIDEⁱ	Q83F36.

PRIDEⁱ

Q83F36.

Interactionⁱ

Subunit structureⁱ

Forms oligomers.UniRule annotation

Protein-protein interaction databases

STRINGⁱ	227377.CBU_0115.

STRINGⁱ

227377.CBU_0115.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q83F36.
SMRⁱ	Q83F36.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	5 – 52	SpoVT-AbrB 1PROSITE-ProRule annotationAdd BLAST		48
Domainⁱ	81 – 124	SpoVT-AbrB 2PROSITE-ProRule annotationAdd BLAST		44

Sequence similaritiesⁱ

Belongs to the MraZ family.UniRule annotation

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	ENOG4108V6E. Bacteria. COG2001. LUCA.
HOGENOMⁱ	HOG000283907.
KEGG Orthology (KO) More...KOⁱ	K03925.
OMAⁱ	CELDGNG.

Family and domain databases

HAMAPⁱ	MF_01008. MraZ. 1 hit.
InterProⁱ	View protein in InterPro IPR003444. MraZ. IPR020603. MraZ_dom. IPR007159. SpoVT-AbrB_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02381. MraZ. 2 hits.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD006745. MraZ. 1 hit.
TIGRFAMsⁱ	TIGR00242. TIGR00242. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51740. SPOVT_ABRB. 2 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q83F36-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFRGLNPIAV DAKGRIAIPA RYREPIESEA DGILVVTIDT EERCLLIYTH 
        60         70         80         90        100
PQWEQIEQKL ENLPSYHPAS RRIQRLLIGH ATEVELDRSG RILIPPVLRE 
       110        120        130        140        150
YAGLGSMVML VGQGKKFELW GKSQWETARE DWLAEELPKG DDLPPELRSL 

SL

Length:152

Mass (Da):17,339

Last modified:June 1, 2003 - v1

Checksum:ⁱB4DDECD1A6A64B59

GO

Sequence cautionⁱ

The sequence AAO89679 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE016828 Genomic DNA. Translation: AAO89679.2. Different initiation.
NCBI Reference Sequences More...RefSeqⁱ	NP_819165.2. NC_002971.3. WP_005769445.1. NZ_CDBG01000001.1. WP_010957389.1. NC_002971.4.

Genome annotation databases

EnsemblBacteriaⁱ	AAO89679; AAO89679; CBU_0115.
GeneIDⁱ	1207986.
KEGGⁱ	cbu:CBU_0115.
PATRICⁱ	17928915. VBICoxBur82552_0118.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE016828 Genomic DNA. Translation: AAO89679.2. Different initiation.
NCBI Reference Sequences More...RefSeqⁱ	NP_819165.2. NC_002971.3. WP_005769445.1. NZ_CDBG01000001.1. WP_010957389.1. NC_002971.4.

3D structure databases

ProteinModelPortalⁱ	Q83F36.
SMRⁱ	Q83F36.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	227377.CBU_0115.

STRINGⁱ

227377.CBU_0115.

Proteomic databases

PRIDEⁱ	Q83F36.

PRIDEⁱ

Q83F36.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAO89679; AAO89679; CBU_0115.
GeneIDⁱ	1207986.
KEGGⁱ	cbu:CBU_0115.
PATRICⁱ	17928915. VBICoxBur82552_0118.

Phylogenomic databases

eggNOGⁱ	ENOG4108V6E. Bacteria. COG2001. LUCA.
HOGENOMⁱ	HOG000283907.
KEGG Orthology (KO) More...KOⁱ	K03925.
OMAⁱ	CELDGNG.

Family and domain databases

HAMAPⁱ	MF_01008. MraZ. 1 hit.
InterProⁱ	View protein in InterPro IPR003444. MraZ. IPR020603. MraZ_dom. IPR007159. SpoVT-AbrB_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02381. MraZ. 2 hits.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD006745. MraZ. 1 hit.
TIGRFAMsⁱ	TIGR00242. TIGR00242. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51740. SPOVT_ABRB. 2 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MRAZ_COXBU
Accessionⁱ	Q83F36Primary (citable) accession number: Q83F36
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
	Last sequence update:	June 1, 2003
	Last modified:	May 10, 2017
	This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Coxiella burnetii
Coxiella burnetii (strain RSA 493): entries and gene names
SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q83F36 (MRAZ_COXBU)

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Transcriptional regulator MraZ

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ