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Q83F06 (SECA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecA
Gene names
Name:secA
Ordered Locus Names:CBU_0147
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length913 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane By similarity. HAMAP-Rule MF_01382

Cofactor

May bind 1 zinc ion per subunit Potential.

Subunit structure

Monomer and homodimer By similarity. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity. HAMAP-Rule MF_01382

Subcellular location

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cytoplasm By similarity. Note: Distribution is 50-50 By similarity. HAMAP-Rule MF_01382

Sequence similarities

Belongs to the SecA family.

Sequence caution

The sequence AAO89711.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 913913Protein translocase subunit SecA HAMAP-Rule MF_01382
PRO_0000320787

Regions

Nucleotide binding102 – 1098ATP Potential

Sites

Metal binding8971Zinc Potential
Metal binding8991Zinc Potential
Metal binding9081Zinc Potential
Metal binding9091Zinc Potential

Sequences

Sequence LengthMass (Da)Tools
Q83F06 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E98BDF59F6CFC2D7

FASTA913103,879
        10         20         30         40         50         60 
MLGNIIKKAF GTRNERLLKG YSKIVSRINA LEPEIQALSD ADLRAKTDEF KKRLVDGEGL 

        70         80         90        100        110        120 
DALLPEAFAV VRETSVRTLG LRHFDVQIIG GLALHGGKIA EMRTGEGKTL GATMPAYLNA 

       130        140        150        160        170        180 
LTGKGVHIVT VNDYLAKRDA EWMKPIYEFL GLTVGVNVPG MEPVEKQAAY AADITYGTNN 

       190        200        210        220        230        240 
EFGFDYLRDN MVFDLDQRVQ RPLHYAIIDE VDSILIDEAR TPLIISGQAE ESSDLYVKIN 

       250        260        270        280        290        300 
KFIPQLKLQK MEEGQKEEEV PPENRGDYTL DEKNRQAYLT EQGHRTIEAL MIKQGLMQAG 

       310        320        330        340        350        360 
ESLYDVSNIS LMHYVYAALR AHTLFYRDVH YIVKNNEVII VDEHTGRLMP GRRWSDGLHQ 

       370        380        390        400        410        420 
AVEAKEGATI QLENQTLATI TFQNYFRLYE KLSGMTATAD TEAFELQKIY GLEVVVIPTN 

       430        440        450        460        470        480 
RPMIRRDESD QVYLTADAKF DAIVNEVKKR HEKGQPLLIG TASIEASELV ARFLKKANIK 

       490        500        510        520        530        540 
HEILNAKNHE REAKIIAEAG RPGAVTIATN MAGRGTDIVL GGNLEAEMSE LDNLAEEEIQ 

       550        560        570        580        590        600 
KRKADWQKRH DAVIAAGGLH VLGTERHESR RIDNQLRGRS GRQGDPGSSQ FYLSMEDNLL 

       610        620        630        640        650        660 
RIFAAERMSN MMRRLGVKED DVIEHPWITR AIEKAQRRVE GMNFDIRKQL LEYDDVANDQ 

       670        680        690        700        710        720 
RKVIYQQRFQ LLQTDDISET IEAIREEAVS EMISSFVPPQ SLEEEWDIPG LEKQIREDFG 

       730        740        750        760        770        780 
LALPIAQWLE KDETLHEETL HKRIIDEITK AYKAKEAKAD PKAMREVEKT LMLQLLDHHW 

       790        800        810        820        830        840 
KEHLAAMDHL RQGIHLRGYA QKNPAQEYKR ESFELFTQML KRIKYELAAT LSKLEIATEE 

       850        860        870        880        890        900 
QVAQQQRLYQ QSAPELQYHH AEMTALQPEK EVAVAEQEEA TQPFVRSQPK VGRNESCPCG 

       910 
SGKKYKQCHG KLS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO89711.2. Different initiation.
RefSeqNP_819197.2. NC_002971.3.

3D structure databases

ProteinModelPortalQ83F06.
SMRQ83F06. Positions 10-841.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_0147.

Proteomic databases

PRIDEQ83F06.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO89711; AAO89711; CBU_0147.
GeneID1208018.
KEGGcbu:CBU_0147.
PATRIC17928977. VBICoxBur82552_0149.

Phylogenomic databases

eggNOGCOG0653.
HOGENOMHOG000218168.
KOK03070.
OMAEAYEFQQ.
OrthoDBEOG654P48.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-148-MONOMER.

Family and domain databases

Gene3D1.10.3060.10. 1 hit.
3.40.50.300. 3 hits.
3.90.1440.10. 1 hit.
HAMAPMF_01382. SecA.
InterProIPR027417. P-loop_NTPase.
IPR004027. SEC_C_motif.
IPR000185. SecA.
IPR020937. SecA_CS.
IPR011115. SecA_DEAD.
IPR014018. SecA_motor_DEAD.
IPR011130. SecA_preprotein_X-link_dom.
IPR011116. SecA_Wing/Scaffold.
[Graphical view]
PfamPF02810. SEC-C. 1 hit.
PF07517. SecA_DEAD. 1 hit.
PF01043. SecA_PP_bind. 1 hit.
PF07516. SecA_SW. 1 hit.
[Graphical view]
PRINTSPR00906. SECA.
SMARTSM00957. SecA_DEAD. 1 hit.
SM00958. SecA_PP_bind. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 3 hits.
SSF81767. SSF81767. 1 hit.
SSF81886. SSF81886. 2 hits.
TIGRFAMsTIGR00963. secA. 1 hit.
PROSITEPS01312. SECA. 1 hit.
PS51196. SECA_MOTOR_DEAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSECA_COXBU
AccessionPrimary (citable) accession number: Q83F06
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names