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Q83ET0 (RPOC_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'

Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:CBU_0232
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length1414 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14141414DNA-directed RNA polymerase subunit beta' HAMAP-Rule MF_01322
PRO_0000067738

Sequences

Sequence LengthMass (Da)Tools
Q83ET0 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: A89BD7F533E3A5BE

FASTA1,414157,104
        10         20         30         40         50         60 
MRDLVKQLKS EKHTAEFDAL RIKLASPEEV RSWSYGEVKK PETINYRTFK PEREGLFCAK 

        70         80         90        100        110        120 
IFGPIKDYEC LCGKYKRLKH RGVICEKCGV EVTLAKVRRE RMGHIELASP VAHIWYLKSL 

       130        140        150        160        170        180 
PSRIGLLLDV TLRDIERILY FEAYVVVDPG MTDLEPRQLL SEEAYLDALE EYGDDFTALM 

       190        200        210        220        230        240 
GAEAIQRLLR DIDVEAEVEA LRTELQTTTS ETKTKKLTKR LKVLSAFLES GNKPEWMILT 

       250        260        270        280        290        300 
VLPVLPPDLR PLVPLDGGRF ATSDLNDLYR RVINRNNRLK RLLDLNAPDI IVRNEKRMLQ 

       310        320        330        340        350        360 
EAVDALLDNG RRGRAILGSN RRQLKSLADM IKGKSGRFRQ NLLGKRVDYS GRSVIVVGPT 

       370        380        390        400        410        420 
LKLHQAGLPK KMALELFKPF IFSKLQLRGL ATTVKAAKKL VENEGPEVWD ILEEVIREHP 

       430        440        450        460        470        480 
ILLNRAPTLH RLGIQAFEPV LVEGKAIQLH PLVCTAYNAD FDGDQMAVHV PLTLEAQLEA 

       490        500        510        520        530        540 
RSLMMSTNNV LHPANGEPII VPSQDVVLGL YYITRDRVNA KGEGMRFADA QEVVRAYEND 

       550        560        570        580        590        600 
QVDLHARITV RIKEGILNEA GEIEESDRLV NTAAGRILLW QIVPKGLPFA LVDQPMTKKA 

       610        620        630        640        650        660 
VTKLLDFCYR NLGLKTTVIF ADKLMYMGFH YATHSGVSIG INDLVVPDQK EAIISRAEDE 

       670        680        690        700        710        720 
VREIEKQYAS GLVTHGERRN KVIDIWSRTN DQVAKAMMEK IAVEKVKDAE GKEVAQSSFN 

       730        740        750        760        770        780 
SIYMMSDSGA RGSAAQTRQL AGMRGLMARP DGTIIETPIT ANFREGLNVL QYFISTHGAR 

       790        800        810        820        830        840 
KGLADTALKT ANSGYLTRRL VDVAQDLVVT EHDCGTEASI EMMPHIEGGD VVEPLRERVL 

       850        860        870        880        890        900 
GRILAEPVMD PKSRKELLAK DTFLDERRVD ILEEHSIDRV RVRSAITCEA RYGICSMCYG 

       910        920        930        940        950        960 
RDLARGHVVN VGEAIGVVAA QSIGEPGTQL TMRTFHIGGA ASRATAANNI GVKSTGKIKL 

       970        980        990       1000       1010       1020 
RNLKTVEQAQ GNLVAVSRSG ELVVQDLQGS EREHYKVPYG ATISVRDGDS VKAGQIVAQW 

      1030       1040       1050       1060       1070       1080 
DPHTHPIITE VAGTLRFVDL VDGVTMNRQT DELTGLSSIV ITSTKQRSAS GKELRPMVKL 

      1090       1100       1110       1120       1130       1140 
VDKNDDDLFL PGGKVPAHYF LPEGTFLTKE DGTTVNIGDV LARIPQETSK TRDITGGLPR 

      1150       1160       1170       1180       1190       1200 
VADLFEARRP KDAAILAEIS GVVSFGKDTK DKGRLIITAP DGTTHEELIP KWRHVSVFEG 

      1210       1220       1230       1240       1250       1260 
ETVEKGEVIA DGPRDPHDIL RLLGVNALAN YIVNEVQEVY RLQGVKINDK HIEVIVRQML 

      1270       1280       1290       1300       1310       1320 
RKVKITQPGD TDLLQNEQVE RTRVREENEK IIKKDGTVAK VEPILLGITK ASLATESFIS 

      1330       1340       1350       1360       1370       1380 
AASFQETTRV LTAASVAGKR DDLRGLKENV IVGRLIPAGT GFSYHQQRRA VAGKSVEEKE 

      1390       1400       1410 
IEEKRVTASE AEQALSEALK SSAPQEAKAA QKDE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO89790.1.
RefSeqNP_819276.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83ET0.
SMRQ83ET0. Positions 16-165, 939-1128.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_0232.

Proteomic databases

PRIDEQ83ET0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO89790; AAO89790; CBU_0232.
GeneID1208113.
KEGGcbu:CBU_0232.
PATRIC17929155. VBICoxBur82552_0226.

Phylogenomic databases

eggNOGCOG0086.
HOGENOMHOG000218386.
KOK03046.
OMAIYFAAYM.
OrthoDBEOG6M9DS6.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-238-MONOMER.

Family and domain databases

HAMAPMF_01322. RNApol_bact_RpoC.
MF_01323. RNApol_bact_RpoC1.
InterProIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_COXBU
AccessionPrimary (citable) accession number: Q83ET0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names