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Protein

DNA-directed RNA polymerase subunit beta'

Gene

rpoC

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Enzyme and pathway databases

BioCyciCBUR227377:G1G0B-237-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit beta'UniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit beta'UniRule annotation
Alternative name(s):
RNA polymerase subunit beta'UniRule annotation
Transcriptase subunit beta'UniRule annotation
Gene namesi
Name:rpoCUniRule annotation
Ordered Locus Names:CBU_0232
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000677381 – 1414DNA-directed RNA polymerase subunit beta'Add BLAST1414

Proteomic databases

PRIDEiQ83ET0

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_0232

Structurei

3D structure databases

ProteinModelPortaliQ83ET0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D27 Bacteria
COG0086 LUCA
HOGENOMiHOG000218386
KOiK03046
OMAiYFAAYMI

Family and domain databases

Gene3Di1.10.132.30, 1 hit
HAMAPiMF_01322 RNApol_bact_RpoC, 1 hit
InterProiView protein in InterPro
IPR012754 DNA-dir_RpoC_beta_prime
IPR000722 RNA_pol_asu
IPR006592 RNA_pol_N
IPR007080 RNA_pol_Rpb1_1
IPR007066 RNA_pol_Rpb1_3
IPR007083 RNA_pol_Rpb1_4
IPR007081 RNA_pol_Rpb1_5
IPR038120 Rpb1_funnel_sf
PfamiView protein in Pfam
PF04997 RNA_pol_Rpb1_1, 1 hit
PF00623 RNA_pol_Rpb1_2, 1 hit
PF04983 RNA_pol_Rpb1_3, 1 hit
PF05000 RNA_pol_Rpb1_4, 1 hit
PF04998 RNA_pol_Rpb1_5, 1 hit
SMARTiView protein in SMART
SM00663 RPOLA_N, 1 hit
TIGRFAMsiTIGR02386 rpoC_TIGR, 1 hit

Sequencei

Sequence statusi: Complete.

Q83ET0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDLVKQLKS EKHTAEFDAL RIKLASPEEV RSWSYGEVKK PETINYRTFK
60 70 80 90 100
PEREGLFCAK IFGPIKDYEC LCGKYKRLKH RGVICEKCGV EVTLAKVRRE
110 120 130 140 150
RMGHIELASP VAHIWYLKSL PSRIGLLLDV TLRDIERILY FEAYVVVDPG
160 170 180 190 200
MTDLEPRQLL SEEAYLDALE EYGDDFTALM GAEAIQRLLR DIDVEAEVEA
210 220 230 240 250
LRTELQTTTS ETKTKKLTKR LKVLSAFLES GNKPEWMILT VLPVLPPDLR
260 270 280 290 300
PLVPLDGGRF ATSDLNDLYR RVINRNNRLK RLLDLNAPDI IVRNEKRMLQ
310 320 330 340 350
EAVDALLDNG RRGRAILGSN RRQLKSLADM IKGKSGRFRQ NLLGKRVDYS
360 370 380 390 400
GRSVIVVGPT LKLHQAGLPK KMALELFKPF IFSKLQLRGL ATTVKAAKKL
410 420 430 440 450
VENEGPEVWD ILEEVIREHP ILLNRAPTLH RLGIQAFEPV LVEGKAIQLH
460 470 480 490 500
PLVCTAYNAD FDGDQMAVHV PLTLEAQLEA RSLMMSTNNV LHPANGEPII
510 520 530 540 550
VPSQDVVLGL YYITRDRVNA KGEGMRFADA QEVVRAYEND QVDLHARITV
560 570 580 590 600
RIKEGILNEA GEIEESDRLV NTAAGRILLW QIVPKGLPFA LVDQPMTKKA
610 620 630 640 650
VTKLLDFCYR NLGLKTTVIF ADKLMYMGFH YATHSGVSIG INDLVVPDQK
660 670 680 690 700
EAIISRAEDE VREIEKQYAS GLVTHGERRN KVIDIWSRTN DQVAKAMMEK
710 720 730 740 750
IAVEKVKDAE GKEVAQSSFN SIYMMSDSGA RGSAAQTRQL AGMRGLMARP
760 770 780 790 800
DGTIIETPIT ANFREGLNVL QYFISTHGAR KGLADTALKT ANSGYLTRRL
810 820 830 840 850
VDVAQDLVVT EHDCGTEASI EMMPHIEGGD VVEPLRERVL GRILAEPVMD
860 870 880 890 900
PKSRKELLAK DTFLDERRVD ILEEHSIDRV RVRSAITCEA RYGICSMCYG
910 920 930 940 950
RDLARGHVVN VGEAIGVVAA QSIGEPGTQL TMRTFHIGGA ASRATAANNI
960 970 980 990 1000
GVKSTGKIKL RNLKTVEQAQ GNLVAVSRSG ELVVQDLQGS EREHYKVPYG
1010 1020 1030 1040 1050
ATISVRDGDS VKAGQIVAQW DPHTHPIITE VAGTLRFVDL VDGVTMNRQT
1060 1070 1080 1090 1100
DELTGLSSIV ITSTKQRSAS GKELRPMVKL VDKNDDDLFL PGGKVPAHYF
1110 1120 1130 1140 1150
LPEGTFLTKE DGTTVNIGDV LARIPQETSK TRDITGGLPR VADLFEARRP
1160 1170 1180 1190 1200
KDAAILAEIS GVVSFGKDTK DKGRLIITAP DGTTHEELIP KWRHVSVFEG
1210 1220 1230 1240 1250
ETVEKGEVIA DGPRDPHDIL RLLGVNALAN YIVNEVQEVY RLQGVKINDK
1260 1270 1280 1290 1300
HIEVIVRQML RKVKITQPGD TDLLQNEQVE RTRVREENEK IIKKDGTVAK
1310 1320 1330 1340 1350
VEPILLGITK ASLATESFIS AASFQETTRV LTAASVAGKR DDLRGLKENV
1360 1370 1380 1390 1400
IVGRLIPAGT GFSYHQQRRA VAGKSVEEKE IEEKRVTASE AEQALSEALK
1410
SSAPQEAKAA QKDE
Length:1,414
Mass (Da):157,104
Last modified:June 1, 2003 - v1
Checksum:iA89BD7F533E3A5BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA Translation: AAO89790.1
RefSeqiNP_819276.1, NC_002971.3
WP_010957448.1, NC_002971.4

Genome annotation databases

EnsemblBacteriaiAAO89790; AAO89790; CBU_0232
GeneIDi1208113
KEGGicbu:CBU_0232
PATRICifig|227377.7.peg.226

Similar proteinsi

Entry informationi

Entry nameiRPOC_COXBU
AccessioniPrimary (citable) accession number: Q83ET0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health