Reviewed, UniProtKB/Swiss-Prot Q83ES7 (EFG_COXBU)

Names and origin

Protein names

Recommended name:
    Elongation factor G
      Short name=EF-G

Gene names

Name:	fusA
Ordered Locus Names:	CBU_0235

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. HAMAP MF_00054
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	GTP-binding Nucleotide-binding
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 699	699	Elongation factor G HAMAP MF_00054		PRO_0000091114
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity
	Nucleotide binding	90 – 94	5	GTP By similarity
	Nucleotide binding	144 – 147	4	GTP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q83ES7-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 88D6509939F8193D	FASTA	699	77,733
	10 20 30 40 50 60 MATAREIPLN RTRNIGIMAH IDAGKTTTTE RVLYYTGVSH KMGEVHEGSA VMDWMEQEQE 70 80 90 100 110 120 RGITITSAAT TCYWLGMDQQ YPKHRINIID TPGHVDFTIE VERSLRVLDG AVAVFCSVGG 130 140 150 160 170 180 VEPQSETVWR QANRYHVPRL GFVNKMDRAG ANFLRVVNQV KDRLNANPIP IQLPIGAEED 190 200 210 220 230 240 FKGVIDLIRE KAIYWNEADR GRTYELADIP EDMKAEVQKW REKMIEAAAE SSEELMDKYL 250 260 270 280 290 300 EAGDLSPEQI RQGLRQRTLA NEIVPILCGS AFKNKGVQAL LDAVIDYLPS PTDVPAIRGE 310 320 330 340 350 360 EDDGSEGSRS ASDDEPFAAL AFKIASDPFV GTLTFFRVYS GILKSGDSVY NPIKGKKERI 370 380 390 400 410 420 GRLLQMHSNS REEIKEVRAG DIAAAVGLKT VTTGDTICNQ QNIITLEKMD FPEPVISVAI 430 440 450 460 470 480 EPKTKADQEK MGVALGKLAQ EDPSFRVHTD EESAQTIIEG MGELHLEIIV DRMRREFNVE 490 500 510 520 530 540 ANVGKPRVAY RETIRRSVEQ QGKYIRQTGG RGQYGDVWLR IEPREPGAGF EFENAIVGGV 550 560 570 580 590 600 VPREYIPAVE KGVREQMENG IRAGYPVVDV KVTIFEGSYH DVDSSEMAFK IAGSMAFKEG 610 620 630 640 650 660 ASKADPVLLE PIMKVEVVTP EEYMGDVVGD LNRRRGMIQG MDESPAGKIV DVEVPLAEMF 670 680 690 GYATDLRSLS QGRATYTMEF LKYAEAPSNI AEAIIKQQS

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO89793.1.
RefSeq	NP_819279.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1208116.
GenomeReviews	Gene locus CBU_0235 in contig AE016828_GR.
KEGG	cbu:CBU_0235.
NMPDR	fig|227377.1.peg.223.
TIGR	CBU_0235.
Phylogenomic databases
HOGENOM	Q83ES7.
OMA	CNEWREK
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0235-MON.
Family and domain databases
HAMAP	MF_00054. [Tree]
InterPro	IPR009022. Elongation_fac_G/III/V. IPR000795. ProtSyn_GTP_bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR005225. Small_GTP_bd. IPR004540. Transl_elong_EFG/EF2. IPR000640. Transl_elong_EFG/EF2_C. IPR005517. Transl_elong_EFG/EF2_IV. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.30.70.240. Transl_elong_EFG/EF2_C. 1 hit.
Pfam	PF00679. EFG_C. 1 hit. PF03764. EFG_IV. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SMART	SM00838. EFG_C. 1 hit. SM00889. EFG_IV. 1 hit. [Graphical view]
TIGRFAMs	TIGR00484. EF-G. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFG_COXBU

Accession

Primary (citable) accession number: Q83ES7

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 29, 2003
Last sequence update:	June 1, 2003
Last modified:	November 24, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)