Q83ES4 (RL3_COXBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L3

Gene names

Name:	rplC
Ordered Locus Names:	CBU_0238

Organism

Coxiella burnetii

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP MF_01325_B
Subunit structure	Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19 By similarity.
Post-translational modification	Methylated by PrmB By similarity. HAMAP MF_01325_B
Sequence similarities	Belongs to the ribosomal protein L3P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Methylation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 217	217	50S ribosomal protein L3 HAMAP MF_01325_B		PRO_0000077096
Amino acid modifications
	Modified residue	153	1	N5-methylglutamine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q83ES4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 89C4813CA125DD9D	FASTA	217	23,508
	10 20 30 40 50 60 MSIGLIGRKC GMTRIFTETG SSIPVTVVEV ILNRITQVKT VETDGYRAFQ VAYGKKSSAR 70 80 90 100 110 120 VNKPLAGHYS KAAVEAGNAL REFRLGNEEL TEAKAGDELK VDIFKEGQVV DVRGLTRGKG 130 140 150 160 170 180 FAGTVKRHNF RTQDATHGNS LSHRAPGSIG QCQTPGRVWK GKKMAGQLGN VYCTVQSQEI 190 200 210 IKVDVERNLL LIKGALPGAP GGEVIITQSS KKRKEDK

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016828 Genomic DNA. Translation: AAO89796.1.
RefSeq	NP_819282.1. NC_002971.3.
3D structure databases
ProteinModelPortal	Q83ES4.
SMR	Q83ES4. Positions 3-211.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1208119.
GenomeReviews	Gene locus CBU_0238 in contig AE016828_GR.
KEGG	cbu:CBU_0238.
NMPDR	fig|227377.1.peg.226.
PATRIC	17929169. VBICoxBur82552_0233.
TIGR	CBU_0238.
Phylogenomic databases
HOGENOM	HBG734653.
OMA	VGMTRLF.
PhylomeDB	Q83ES4.
ProtClustDB	PRK00001.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0238-MONOMER.
Family and domain databases
HAMAP	MF_01325_B. Ribosomal_L3_B. [Tree]
InterPro	IPR000597. Ribosomal_L3. IPR019927. Ribosomal_L3_bac/org-type. IPR019926. Ribosomal_L3_CS. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
KO	K02906.
PANTHER	PTHR11229. PTHR11229. 1 hit.
Pfam	PF00297. Ribosomal_L3. 1 hit. [Graphical view]
SUPFAM	SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR03625. L3_bact. 1 hit.
PROSITE	PS00474. RIBOSOMAL_L3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL3_COXBU

Accession

Primary (citable) accession number: Q83ES4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program