Q83ES3 (RL4_COXBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L4

Gene names

Name:	rplD
Ordered Locus Names:	CBU_0239

Organism

Coxiella burnetii

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP MF_01328_B Forms part of the polypeptide exit tunnel By similarity. HAMAP MF_01328_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L4P family.
Sequence caution	The sequence AAO89797.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	50S ribosomal protein L4 HAMAP MF_01328_B		PRO_0000129213

Sequences

	Sequence		Length	Mass (Da)
	Q83ES3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 0EF928AB6850122E	FASTA	205	22,374
	10 20 30 40 50 60 MELPVNSFDK KEASTLTVAD SAFGSEYKEG LVHQVVNAYL AGGRAGTKAQ KTRREVSGGG 70 80 90 100 110 120 AKPWRQKGTG RARAGSSRSP LWRSGGVAFA AKPRDFTQKV NRKMYRSAMA SILSELIRRE 130 140 150 160 170 180 QLVVVDSLKL NEPKTRELKE SLKKLNLGNV LIIIDGDDRN INLASRNMVG VSVCDALHVD 190 200 PVSLVAAENI VVTVDAVKRL EERLS

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016828 Genomic DNA. Translation: AAO89797.2. Different initiation.
RefSeq	NP_819283.2. NC_002971.3.
3D structure databases
ProteinModelPortal	Q83ES3.
SMR	Q83ES3. Positions 1-205.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1208120.
GenomeReviews	Gene locus CBU_0239 in contig AE016828_GR.
KEGG	cbu:CBU_0239.
NMPDR	fig|227377.1.peg.227.
PATRIC	17929171. VBICoxBur82552_0234.
TIGR	CBU_0239.
Phylogenomic databases
HOGENOM	HBG545479.
OMA	LPIQGIN.
PhylomeDB	Q83ES3.
ProtClustDB	PRK05319.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0239-MONOMER.
Family and domain databases
HAMAP	MF_01328_B. Ribosomal_L4_B. [Tree]
InterPro	IPR002136. Ribosomal_L4/L1e. IPR013005. Ribosomal_L4/L1e_bac-type. IPR023574. Ribosomal_L4_dom. [Graphical view]
Gene3D	G3DSA:3.40.1370.10. G3DSA:3.40.1370.10. 1 hit.
KO	K02926.
PANTHER	PTHR10746. Ribos_L4_L1E_bac. 1 hit.
Pfam	PF00573. Ribosomal_L4. 1 hit. [Graphical view]
SUPFAM	SSF52166. Ribosomal_L4/L1E. 1 hit.
TIGRFAMs	TIGR03953. RplD_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL4_COXBU

Accession

Primary (citable) accession number: Q83ES3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program