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Q83EL9 (RNPH_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease PH

Short name=RNase PH
EC=2.7.7.56
Alternative name(s):
tRNA nucleotidyltransferase
Gene names
Name:rph
Ordered Locus Names:CBU_0299
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP-Rule MF_00564

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP-Rule MF_00564

Sequence similarities

Belongs to the RNase PH family.

Sequence caution

The sequence AAO89856.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Ribonuclease PH HAMAP-Rule MF_00564
PRO_0000139886

Sequences

Sequence LengthMass (Da)Tools
Q83EL9 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 445F30D58D5B4744

FASTA23725,971
        10         20         30         40         50         60 
MRPSKRAANE LRPLSFTTQF TRYAEGSVLV TLGNTKVICN ASIVEGVPRF LKNSEQGWLT 

        70         80         90        100        110        120 
AEYGMLPRST HSRMDREASR GKQGGRTVEI QRLIGRSLRA ALDLKLLGPY TITIDCDVIQ 

       130        140        150        160        170        180 
ADGGTRTAAI NGSCIAMIEA LRHLQRKGIL QTDPLKHKVA AVSVGIYKGV PVLDLDYAED 

       190        200        210        220        230 
SNAHTDMNVV MTDNDAFIEI QGTAEGDAFH AKELDALINL ARHGIKQIIE KQQEALS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO89856.2. Different initiation.
RefSeqNP_819342.2. NC_002971.3.

3D structure databases

ProteinModelPortalQ83EL9.
SMRQ83EL9. Positions 2-237.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_0299.

Proteomic databases

PRIDEQ83EL9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO89856; AAO89856; CBU_0299.
GeneID1208181.
KEGGcbu:CBU_0299.
PATRIC17929293. VBICoxBur82552_0294.

Phylogenomic databases

eggNOGCOG0689.
HOGENOMHOG000229516.
KOK00989.
OMAKGQGWVT.
OrthoDBEOG6CZQQP.
ProtClustDBPRK00173.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-306-MONOMER.

Family and domain databases

Gene3D3.30.230.70. 1 hit.
HAMAPMF_00564. RNase_PH.
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPH_COXBU
AccessionPrimary (citable) accession number: Q83EL9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names