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Q83EL7 (KGUA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Guanylate kinase
EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:CBU_0301
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella ›

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

guanylate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170530

Regions

Domain4 – 182179Guanylate kinase-like
Nucleotide binding11 – 188ATP By similarity

Secondary structure

1 .................................. 206
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q83EL7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 815BFEA7481A0D9C

FASTA20623,809
        10         20         30         40         50         60 
MNKANLFIIS APSGAGKTSL VRALVKALAE IKISISHTTR PKRPGDQEGV DYFFIDETRF 

        70         80         90        100        110        120 
QAMVKEGAFL EHATIYERHY GTEKDWVLRQ LKAGRDVLLE IDWQGARQIR ELFPPALSIF 

       130        140        150        160        170        180 
ILPPSIEALR ERLIKRRQDD TAIIEQRLAL AREEMAHYKE FDYLVVNDNF DQAVQNLIHI 

       190        200 
ISAERLQRDV QEKKLSRLLA ELVEKQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016828 Genomic DNA. Translation: AAO89858.1.
RefSeqNP_819344.1. NC_002971.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3TR0X-ray1.85A1-202[»]
ProteinModelPortalQ83EL7.
ModBaseSearch...

Protein-protein interaction databases

STRING227377.CBU_0301.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO89858; AAO89858; CBU_0301.
GeneID1208183.
KEGGcbu:CBU_0301.
PATRIC17929297. VBICoxBur82552_0296.

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037638.
KOK00942.
OMAFVIINEL.
ProtClustDBPRK00300.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-308-MONOMER.

Family and domain databases

HAMAPMF_00328. Guanylate_kinase.
InterProIPR008144. Guanylate_kin.
IPR008145. Guanylate_kin/L-typ_Ca_channel.
IPR020590. Guanylate_kinase_CS.
IPR017665. Guanylate_kinase_sub.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_COXBU
AccessionPrimary (citable) accession number: Q83EL7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: May 29, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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