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Q83EL0 (HTPG_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein HtpG
Alternative name(s):
Heat shock protein HtpG
High temperature protein G
Gene names
Name:htpG
Ordered Locus Names:CBU_0309
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length633 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Molecular chaperone. Has ATPase activity By similarity. HAMAP-Rule MF_00505

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00505

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00505.

Developmental stage

More than twofold more abundant in the large cell variant (LCV) stage than in the small cell variant (SCV) stage (at protein level). LCVs are more metabolically active than SCVs. Ref.2

Sequence similarities

Belongs to the heat shock protein 90 family.

Sequence caution

The sequence AAO89866.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 633633Chaperone protein HtpG HAMAP-Rule MF_00505
PRO_0000062984

Regions

Region1 – 344344A; substrate-binding By similarity
Region345 – 560216B By similarity
Region561 – 63373C By similarity

Sequences

Sequence LengthMass (Da)Tools
Q83EL0 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: BC71210DD4B52271

FASTA63372,774
        10         20         30         40         50         60 
MSLQPQAETL SFEAEVKQLL HLVAHSLYSN KEIFLRELIS NSSDAADKLR YQALSDAALY 

        70         80         90        100        110        120 
ENDADLKIWI DFDKDNRTIT IRDNGIGMSR EEVIENLGTI AKSGTRAFRE LLAEKKAEDS 

       130        140        150        160        170        180 
QLIGQFGVGF YSAFIVADRV VVRTRRAGMK ADQGVEWEST GEGEYTLKNI DKPTRGTEVV 

       190        200        210        220        230        240 
LHLKESEEEF LDPLRLRAII TKYSDHILLP IVMKKIKTSG ADDEDKNETP EEEVVNRANA 

       250        260        270        280        290        300 
LWVLPKDKIK DEEYKELYKH IAHDFEDPLA WVHNKVEGKL EYTTLLYIPA RAPFDLWNRE 

       310        320        330        340        350        360 
GQRGLKLYVK RIFIMDDAEH FMPMYLRFVK GIVDSNDLPL NISRELLQSN EVINKIKAGC 

       370        380        390        400        410        420 
VKRILSLLED LAKNDKEKYA SFWKAFGQVL KEGPAEDFAN RDRIANLLRF ASTHNDTDEQ 

       430        440        450        460        470        480 
NVSLQDYISR MKPEQNKIYY IVADTYTSAK NSPLLEVFRK KDIEVLLMSD RVDEWLVAHL 

       490        500        510        520        530        540 
NEFEGKSLQS IAKGTLDLGD LEKEEKVETE KFEKDFDELL KQFKEVLGEK IKDVRITHRL 

       550        560        570        580        590        600 
TDSPTCVVFD ENEMSGHLQR LLIQTGQDFM QAKPILEINP SHPLILRVKN ESDKTRFNRW 

       610        620        630 
ADLLLNQALL AEGEQLKDPA SFVKGLNELL LDS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO89866.2. Different initiation.
RefSeqNP_819352.2. NC_002971.3.

3D structure databases

ProteinModelPortalQ83EL0.
SMRQ83EL0. Positions 8-491.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_0309.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO89866; AAO89866; CBU_0309.
GeneID1208191.
KEGGcbu:CBU_0309.
PATRIC17929309. VBICoxBur82552_0302.

Phylogenomic databases

eggNOGCOG0326.
HOGENOMHOG000031989.
KOK04079.
OMALTDSPAC.
OrthoDBEOG65TRNM.
ProtClustDBPRK05218.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-316-MONOMER.

Family and domain databases

Gene3D3.30.565.10. 1 hit.
HAMAPMF_00505. HSP90.
InterProIPR003594. HATPase_ATP-bd.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR027058. HtpG.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF39. PTHR11528:SF39. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFPIRSF002583. Hsp90. 1 hit.
PRINTSPR00775. HEATSHOCK90.
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHTPG_COXBU
AccessionPrimary (citable) accession number: Q83EL0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names