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Q83D67 (AROC_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase

EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:CBU_0874
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP-Rule MF_00300

Cofactor

Reduced flavin By similarity. HAMAP-Rule MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP-Rule MF_00300

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

chorismate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionchorismate synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Chorismate synthase HAMAP-Rule MF_00300
PRO_0000140580

Sequences

Sequence LengthMass (Da)Tools
Q83D67 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 00744BEF3C1AA44B

FASTA35237,949
        10         20         30         40         50         60 
MSGNSFGKLF TVTTAGESHG PALVAIVDGC PAGLSLTEAD IQPDIDRRKT GKSRFTSQRR 

        70         80         90        100        110        120 
ESDQVKILSG VFEGVTTGTP IALLIENADQ RPRDYSQIKD LFRPGHGDYT YFKKYGFRDY 

       130        140        150        160        170        180 
RGGGRASARE TVMRVAAGAI AKKYLREKVN LTIQGYTAAV GAIRAERIDL SAVEKNPFFF 

       190        200        210        220        230        240 
PDEVQIPHLE QLIMKLRRDG DSIGARLNVI AKGVPCGLGE PVFDKLDADI ASAMMGINAV 

       250        260        270        280        290        300 
KGVEIGDGFA VVEQKGSFHR DELSKKGFLS NHAGGTLAGI SSGQDILVSL AFKPASSIRI 

       310        320        330        340        350 
PGKTLDINGK AVEVVTTGRH DPCVGLRAVP IAEAMLALVL MDHYLRYKAQ RG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO90406.1.
RefSeqNP_819892.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83D67.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_0874.

Proteomic databases

PRIDEQ83D67.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO90406; AAO90406; CBU_0874.
GeneID1208767.
KEGGcbu:CBU_0874.
PATRIC17930447. VBICoxBur82552_0860.

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHOG000060335.
KOK01736.
OMAYMRDLKK.
OrthoDBEOG6WDSHT.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-868-MONOMER.
UniPathwayUPA00053; UER00090.

Family and domain databases

Gene3D3.60.150.10. 1 hit.
HAMAPMF_00300. Chorismate_synth.
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
PANTHERPTHR21085. PTHR21085. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. SSF103263. 1 hit.
TIGRFAMsTIGR00033. aroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_COXBU
AccessionPrimary (citable) accession number: Q83D67
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names