Q83CQ4 (RECA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein RecA

Alternative name(s):
Recombinase A

Gene names

Name:	recA
Ordered Locus Names:	CBU_1054

Organism

Coxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]

Taxonomic identifier

227377 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella › Coxiella burnetii

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP-Rule MF_00268
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the RecA family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA-dependent ATPase activity Inferred from electronic annotation. Source: HAMAP damaged DNA binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Protein RecA HAMAP-Rule MF_00268		PRO_0000122699

Sequences

	Sequence		Length	Mass (Da)
	Q83CQ4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A7E05789C0E1C482	FASTA	343	37,128
	10 20 30 40 50 60 MDNRSNALNA ALSQIERQFG KGSVMRLGDP GLIPDIDVIS TGSLGLDIAL GVGGLPRGRI 70 80 90 100 110 120 IEIYGPEASG KTTLALQTIA SCQRMGGTAA FVDAEHALDA IYAGKLGVKV EDLLVSQPDT 130 140 150 160 170 180 GEQALEITDM LVRSGAVDLI VIDSVAALTP KAEIEGDMGD SHMGLQARLM SQALRKLTAN 190 200 210 220 230 240 IKKSNTLVIF INQIRMKIGV MFGNPETTTG GNALKFYSSV RLDIRRIGAI KKGEEILGSE 250 260 270 280 290 300 TRVKVVKNKV APPFRQVEFD ILYGLGISRE SELIDLGVKN ELVEKAGAWY SYNGERIGQG 310 320 330 340 KENVRQFFLE NPKIAGEIET RLREKLLPHR QGEKIAEEVN AAE

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RSA 493 / Nine Mile phase I.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016828 Genomic DNA. Translation: AAO90569.1.
RefSeq	NP_820055.1. NC_002971.3.
3D structure databases
ProteinModelPortal	Q83CQ4.
SMR	Q83CQ4. Positions 2-327.
ModBase	Search...
Protein-protein interaction databases
STRING	227377.CBU_1054.
Proteomic databases
PRIDE	Q83CQ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO90569; AAO90569; CBU_1054.
GeneID	1208955.
KEGG	cbu:CBU_1054.
PATRIC	17930833. VBICoxBur82552_1045.
Phylogenomic databases
eggNOG	COG0468.
HOGENOM	HOG000264120.
KO	K03553.
OMA	MLIFINQ.
ProtClustDB	PRK09354.
Enzyme and pathway databases
BioCyc	CBUR227377:GJ7S-1046-MONOMER.
Family and domain databases
Gene3D	3.30.250.10. 1 hit.
HAMAP	MF_00268. RecA.
InterPro	IPR003593. AAA+_ATPase. IPR013765. DNA_recomb/repair_RecA. IPR020584. DNA_recomb/repair_RecA_CS. IPR020588. DNA_recomb_RecA/RadB_ATP-bd. IPR023400. RecA_C. IPR020587. RecA_monomer-monomer_interface. [Graphical view]
PANTHER	PTHR22942:SF1. PTHR22942:SF1. 1 hit.
Pfam	PF00154. RecA. 1 hit. [Graphical view]
PRINTS	PR00142. RECA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF54752. SSF54752. 1 hit.
TIGRFAMs	TIGR02012. tigrfam_recA. 1 hit.
PROSITE	PS00321. RECA_1. 1 hit. PS50162. RECA_2. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECA_COXBU

Accession

Primary (citable) accession number: Q83CQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2003
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program