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Protein

Translation initiation factor IF-3

Gene

infC

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-3UniRule annotation
Gene namesi
Name:infCUniRule annotation
Ordered Locus Names:CBU_1325
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001775131 – 185Translation initiation factor IF-3Add BLAST185

Proteomic databases

PRIDEiQ83C11.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_1325.

Structurei

3D structure databases

ProteinModelPortaliQ83C11.
SMRiQ83C11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IF-3 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UUX. Bacteria.
COG0290. LUCA.
HOGENOMiHOG000035157.
KOiK02520.
OMAiGRNMIMF.

Family and domain databases

HAMAPiMF_00080. IF_3. 1 hit.
InterProiView protein in InterPro
IPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiView protein in Pfam
PF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiView protein in PROSITE
PS00938. IF3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83C11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSKRTRVNN QIRVPEVRLI DEKGEQVGVV RTDRALTMAE EAGLDLVEIS
60 70 80 90 100
PTAKPPVCRI MNFGKYQFEQ SKRKAAQKKK QRLVHLKEVK FRPGTDVGDY
110 120 130 140 150
QVKLRKIATF LDRGDKVKVS LRFRGREMQH RELGLELLGR VKRDLGNIVV
160 170 180
EQEPRLEGRQ MTMVVMKAKG EGNKTKREDH AEIKD
Length:185
Mass (Da):21,390
Last modified:December 15, 2003 - v2
Checksum:i8D69777F8FD239EE
GO

Sequence cautioni

The sequence AAO90829 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90829.1. Different initiation.
RefSeqiNP_820315.1. NC_002971.3.
WP_005770939.1. NC_002971.4.
WP_061299200.1. NZ_CDBG01000001.1.

Genome annotation databases

EnsemblBacteriaiAAO90829; AAO90829; CBU_1325.
GeneIDi1209231.
31484025.
KEGGicbu:CBU_1325.
PATRICifig|227377.7.peg.1316.

Similar proteinsi

Entry informationi

Entry nameiIF3_COXBU
AccessioniPrimary (citable) accession number: Q83C11
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: September 27, 2017
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. Translation initiation factors
    List of translation initiation factor entries
  3. SIMILARITY comments
    Index of protein domains and families