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Protein

Translation initiation factor IF-3

Gene

infC

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1316-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-3UniRule annotation
Gene namesi
Name:infCUniRule annotation
Ordered Locus Names:CBU_1325
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002671 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Translation initiation factor IF-3PRO_0000177513Add
BLAST

Proteomic databases

PRIDEiQ83C11.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_1325.

Structurei

3D structure databases

ProteinModelPortaliQ83C11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IF-3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0290.
HOGENOMiHOG000035157.
KOiK02520.
OMAiHDFNVKV.
OrthoDBiEOG63JRGJ.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83C11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSKRTRVNN QIRVPEVRLI DEKGEQVGVV RTDRALTMAE EAGLDLVEIS
60 70 80 90 100
PTAKPPVCRI MNFGKYQFEQ SKRKAAQKKK QRLVHLKEVK FRPGTDVGDY
110 120 130 140 150
QVKLRKIATF LDRGDKVKVS LRFRGREMQH RELGLELLGR VKRDLGNIVV
160 170 180
EQEPRLEGRQ MTMVVMKAKG EGNKTKREDH AEIKD
Length:185
Mass (Da):21,390
Last modified:December 15, 2003 - v2
Checksum:i8D69777F8FD239EE
GO

Sequence cautioni

The sequence AAO90829.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90829.1. Different initiation.
RefSeqiNP_820315.1. NC_002971.3.

Genome annotation databases

EnsemblBacteriaiAAO90829; AAO90829; CBU_1325.
GeneIDi1209231.
KEGGicbu:CBU_1325.
PATRICi17931385. VBICoxBur82552_1316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90829.1. Different initiation.
RefSeqiNP_820315.1. NC_002971.3.

3D structure databases

ProteinModelPortaliQ83C11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227377.CBU_1325.

Proteomic databases

PRIDEiQ83C11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO90829; AAO90829; CBU_1325.
GeneIDi1209231.
KEGGicbu:CBU_1325.
PATRICi17931385. VBICoxBur82552_1316.

Phylogenomic databases

eggNOGiCOG0290.
HOGENOMiHOG000035157.
KOiK02520.
OMAiHDFNVKV.
OrthoDBiEOG63JRGJ.

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1316-MONOMER.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 493 / Nine Mile phase I.

Entry informationi

Entry nameiIF3_COXBU
AccessioniPrimary (citable) accession number: Q83C11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: July 22, 2015
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. Translation initiation factors
    List of translation initiation factor entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.