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Protein

Transcriptional repressor NrdR

Gene

nrdR

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3 – 34UniRule annotationAdd BLAST32

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor NrdRUniRule annotation
Gene namesi
Name:nrdRUniRule annotation
Ordered Locus Names:CBU_1418
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001822911 – 157Transcriptional repressor NrdRAdd BLAST157

Proteomic databases

PRIDEiQ83BT4.

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1418.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 139ATP-coneUniRule annotationAdd BLAST91

Sequence similaritiesi

Belongs to the NrdR family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3 – 34UniRule annotationAdd BLAST32

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG4108Z11. Bacteria.
COG1327. LUCA.
HOGENOMiHOG000097653.
KOiK07738.
OMAiRFTTYET.

Family and domain databases

HAMAPiMF_00440. NrdR. 1 hit.
InterProiView protein in InterPro
IPR005144. ATP-cone_dom.
IPR003796. RNR_NrdR-like.
PANTHERiPTHR30455. PTHR30455. 1 hit.
PfamiView protein in Pfam
PF03477. ATP-cone. 1 hit.
TIGRFAMsiTIGR00244. TIGR00244. 1 hit.
PROSITEiView protein in PROSITE
PS51161. ATP_CONE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83BT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYCPFCNAED TKVIDSRLVE EGTQVRRRRE CLKCQERFTT FETAELNLPR
60 70 80 90 100
IIKRDGRRSA FDEEKLRAGL LKALEKRPIS TEQIETAVQR IIHKLRARGE
110 120 130 140 150
CEVSSQWLGE LVMDELRALD EVAYVRFASV YRSFQDINAF RDEIRRLQKQ

QKKSHDK
Length:157
Mass (Da):18,579
Last modified:June 1, 2003 - v1
Checksum:i8D5102E45D9E8579
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90916.1.
RefSeqiNP_820402.1. NC_002971.3.
WP_005771735.1. NZ_CDBG01000001.1.

Genome annotation databases

EnsemblBacteriaiAAO90916; AAO90916; CBU_1418.
GeneIDi1209324.
31483215.
KEGGicbu:CBU_1418.
PATRICifig|227377.7.peg.1418.

Similar proteinsi

Entry informationi

Entry nameiNRDR_COXBU
AccessioniPrimary (citable) accession number: Q83BT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families