Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q83BS1

- IF2_COXBU

UniProt

Q83BS1 - IF2_COXBU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi311 – 3188GTPUniRule annotation
Nucleotide bindingi357 – 3615GTPUniRule annotation
Nucleotide bindingi411 – 4144GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1419-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:CBU_1432
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002671: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 803803Translation initiation factor IF-2PRO_0000137198Add
BLAST

Proteomic databases

PRIDEiQ83BS1.

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1432.

Structurei

3D structure databases

ProteinModelPortaliQ83BS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini302 – 471170tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni311 – 3188G1By similarity
Regioni336 – 3405G2By similarity
Regioni357 – 3604G3By similarity
Regioni411 – 4144G4By similarity
Regioni447 – 4493G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiSTILCFN.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83BS1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADMSVKQLA DLVRTTPERL LEQLKEAGVA ITHVDQTISD EEKRKLLLHL
60 70 80 90 100
KTSHSTETDK KRSKIVLKRK KLSVVKSGKK SVNVEIRSKR TYTKPVVEQK
110 120 130 140 150
RETEPAPTQE VPPTSDTTNL NEKAEVNVAT LEKAVEAEVK EEAKKTPSEK
160 170 180 190 200
KETPKKGPRK ETRRSRKPDK EDKWEREELH MTKLVEERRR RHKPAHMPDS
210 220 230 240 250
DSASAKLEQG FARPTAPVVR EVALPESITV ADLAQKMSVK AAEVIKAMMK
260 270 280 290 300
LGAMVTINQR IDQETAAIVV EEMGHKPKLI KEDVLEENLV ATLGEQTGEA
310 320 330 340 350
VPRAPVVTIM GHVDHGKTSL LDYIRRTKVT STEAGGITQH IGAYHVETEL
360 370 380 390 400
GMITFLDTPG HEAFTAMRAR GAKCTDIVVL VVAADDGVMP QTVEAIQHAR
410 420 430 440 450
AAKVPVVVAV NKIDKPEADP ERIKTELSTH DVLPEEWGGD TMFQPISAKT
460 470 480 490 500
GEGIDALLER ILLQAEVLEL KAVDNGPARG MVVESRLDRG RGPVATVLVT
510 520 530 540 550
SGELHLGDIL LVGREYGRVR AMIGDDGRPC ESAGPSMPVE VLGLSGTSVA
560 570 580 590 600
GEEAIVVPDE RKAREIARFR QGKYREVRLA KKQTAHLERI FDRMGEGKQN
610 620 630 640 650
TLNIVLKADV QGSLEALTEA LNKLSTDEVK VNIIASGVGG ITESDVNLAI
660 670 680 690 700
ASDAVVIGFN VRADAPTRVL VEREGVDLRY YSIIYDLIDE VKKALSGLLA
710 720 730 740 750
PEFEEKIVGL AEVRDVFRSS KIGAIAGCMV VEGVVRRHLP IRVLRDNVVI
760 770 780 790 800
YEGQLESLRR YKEDVAEVRQ GTECGIGVKN YNDVKVGDQI EVYEKTQVHR

TIA
Length:803
Mass (Da):88,486
Last modified:June 1, 2003 - v1
Checksum:i00C73115E6B3D5C9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016828 Genomic DNA. Translation: AAO90929.1.
RefSeqiNP_820415.1. NC_002971.3.
WP_010958223.1. NC_002971.3.

Genome annotation databases

EnsemblBacteriaiAAO90929; AAO90929; CBU_1432.
GeneIDi1209338.
KEGGicbu:CBU_1432.
PATRICi17931615. VBICoxBur82552_1431.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016828 Genomic DNA. Translation: AAO90929.1 .
RefSeqi NP_820415.1. NC_002971.3.
WP_010958223.1. NC_002971.3.

3D structure databases

ProteinModelPortali Q83BS1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 227377.CBU_1432.

Proteomic databases

PRIDEi Q83BS1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO90929 ; AAO90929 ; CBU_1432 .
GeneIDi 1209338.
KEGGi cbu:CBU_1432.
PATRICi 17931615. VBICoxBur82552_1431.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi STILCFN.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci CBUR227377:GJ7S-1419-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 493 / Nine Mile phase I.

Entry informationi

Entry nameiIF2_COXBU
AccessioniPrimary (citable) accession number: Q83BS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3