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Protein

NADH-quinone oxidoreductase subunit B

Gene

nuoB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).By similarity

Catalytic activityi

NADH + a quinone = NAD+ + a quinol.UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi36 – 361Iron-sulfur (4Fe-4S)UniRule annotation
Metal bindingi37 – 371Iron-sulfur (4Fe-4S)UniRule annotation
Metal bindingi102 – 1021Iron-sulfur (4Fe-4S)UniRule annotation
Metal bindingi132 – 1321Iron-sulfur (4Fe-4S)UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, NAD, Ubiquinone

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1435-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit BUniRule annotation (EC:1.6.5.11UniRule annotation)
Alternative name(s):
NADH dehydrogenase I subunit BUniRule annotation
NDH-1 subunit BUniRule annotation
Gene namesi
Name:nuoBUniRule annotation
Ordered Locus Names:CBU_1447
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002671 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 161161NADH-quinone oxidoreductase subunit BPRO_0000358395Add
BLAST

Keywords - PTMi

Quinone

Proteomic databases

PRIDEiQ83BQ6.

Interactioni

Subunit structurei

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_1447.

Structurei

3D structure databases

ProteinModelPortaliQ83BQ6.
SMRiQ83BQ6. Positions 7-158.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 20 kDa subunit family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0377.
HOGENOMiHOG000228249.
KOiK00331.
OMAiDIDRFGM.
OrthoDBiEOG62K20C.

Family and domain databases

Gene3Di3.40.50.700. 1 hit.
HAMAPiMF_01356. NDH1_NuoB.
InterProiIPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR006138. NADH_UQ_OxRdtase_20Kd_su.
[Graphical view]
PfamiPF01058. Oxidored_q6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01957. nuoB_fam. 1 hit.
PROSITEiPS01150. COMPLEX1_20K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q83BQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLLTKEGF LLTSLDDLMR WARSGSLWPM TFGLACCAVE MMQCASSRYD
60 70 80 90 100
LDRFGAGLFR PSPRQSDVMI VAGTLCNKMA PALRKVYDQM AEPRWVISMG
110 120 130 140 150
SCANGGGYYH YAYSVVRGCD RIVPVDVYVP GCPPTAEALF YGIMQLRNKI
160
RYRNIFDRKD A
Length:161
Mass (Da):18,160
Last modified:June 1, 2003 - v1
Checksum:i4720682912477297
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90944.1.
RefSeqiNP_820430.1. NC_002971.3.
WP_005769074.1. NZ_CDBG01000001.1.

Genome annotation databases

EnsemblBacteriaiAAO90944; AAO90944; CBU_1447.
GeneIDi1209354.
KEGGicbu:CBU_1447.
PATRICi17931649. VBICoxBur82552_1447.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO90944.1.
RefSeqiNP_820430.1. NC_002971.3.
WP_005769074.1. NZ_CDBG01000001.1.

3D structure databases

ProteinModelPortaliQ83BQ6.
SMRiQ83BQ6. Positions 7-158.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227377.CBU_1447.

Proteomic databases

PRIDEiQ83BQ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO90944; AAO90944; CBU_1447.
GeneIDi1209354.
KEGGicbu:CBU_1447.
PATRICi17931649. VBICoxBur82552_1447.

Phylogenomic databases

eggNOGiCOG0377.
HOGENOMiHOG000228249.
KOiK00331.
OMAiDIDRFGM.
OrthoDBiEOG62K20C.

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1435-MONOMER.

Family and domain databases

Gene3Di3.40.50.700. 1 hit.
HAMAPiMF_01356. NDH1_NuoB.
InterProiIPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR006138. NADH_UQ_OxRdtase_20Kd_su.
[Graphical view]
PfamiPF01058. Oxidored_q6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01957. nuoB_fam. 1 hit.
PROSITEiPS01150. COMPLEX1_20K. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 493 / Nine Mile phase I.

Entry informationi

Entry nameiNUOB_COXBU
AccessioniPrimary (citable) accession number: Q83BQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.