Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NADH-quinone oxidoreductase subunit B

Gene

nuoB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).By similarity

Catalytic activityi

NADH + a quinone = NAD+ + a quinol.UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi36Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi37Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi102Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi132Iron-sulfur (4Fe-4S)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

  • mitochondrial electron transport, NADH to ubiquinone Source: TIGR

Keywordsi

Molecular functionOxidoreductase
Biological processTransport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding, NAD, Ubiquinone

Enzyme and pathway databases

BioCyciCBUR227377:G1G0B-1433-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit BUniRule annotation (EC:1.6.5.11UniRule annotation)
Alternative name(s):
NADH dehydrogenase I subunit BUniRule annotation
NDH-1 subunit BUniRule annotation
Gene namesi
Name:nuoBUniRule annotation
Ordered Locus Names:CBU_1447
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003583951 – 161NADH-quinone oxidoreductase subunit BAdd BLAST161

Keywords - PTMi

Quinone

Proteomic databases

PRIDEiQ83BQ6

Interactioni

Subunit structurei

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_1447

Structurei

3D structure databases

ProteinModelPortaliQ83BQ6
SMRiQ83BQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 20 kDa subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105ES3 Bacteria
COG0377 LUCA
HOGENOMiHOG000228249
KOiK00331
OMAiEMMTTGA

Family and domain databases

HAMAPiMF_01356 NDH1_NuoB, 1 hit
InterProiView protein in InterPro
IPR006137 NADH_UbQ_OxRdtase-like_20kDa
IPR006138 NADH_UQ_OxRdtase_20Kd_su
PfamiView protein in Pfam
PF01058 Oxidored_q6, 1 hit
TIGRFAMsiTIGR01957 nuoB_fam, 1 hit
PROSITEiView protein in PROSITE
PS01150 COMPLEX1_20K, 1 hit

Sequencei

Sequence statusi: Complete.

Q83BQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLLTKEGF LLTSLDDLMR WARSGSLWPM TFGLACCAVE MMQCASSRYD
60 70 80 90 100
LDRFGAGLFR PSPRQSDVMI VAGTLCNKMA PALRKVYDQM AEPRWVISMG
110 120 130 140 150
SCANGGGYYH YAYSVVRGCD RIVPVDVYVP GCPPTAEALF YGIMQLRNKI
160
RYRNIFDRKD A
Length:161
Mass (Da):18,160
Last modified:June 1, 2003 - v1
Checksum:i4720682912477297
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA Translation: AAO90944.1
RefSeqiNP_820430.1, NC_002971.3
WP_005769074.1, NZ_LM994641.1

Genome annotation databases

EnsemblBacteriaiAAO90944; AAO90944; CBU_1447
GeneIDi1209354
31483183
KEGGicbu:CBU_1447
PATRICifig|227377.7.peg.1447

Similar proteinsi

Entry informationi

Entry nameiNUOB_COXBU
AccessioniPrimary (citable) accession number: Q83BQ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health