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Q83BM5 (AHPD_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alkyl hydroperoxide reductase AhpD

EC=1.11.1.15
Alternative name(s):
Alkylhydroperoxidase AhpD
Gene names
Name:ahpD
Ordered Locus Names:CBU_1478
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity By similarity. HAMAP-Rule MF_01676

Catalytic activity

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP-Rule MF_01676

Sequence similarities

Belongs to the AhpD family.

Sequence caution

The sequence AAO90975.2 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 177177Alkyl hydroperoxide reductase AhpD HAMAP-Rule MF_01676
PRO_0000359485

Sites

Active site1331Proton donor By similarity
Active site1361Cysteine sulfenic acid (-SOH) intermediate By similarity

Amino acid modifications

Disulfide bond133 ↔ 136Alternate By similarity
Disulfide bond136Interchain (with AhpC); in linked form By similarity

Sequences

Sequence LengthMass (Da)Tools
Q83BM5 [UniParc].

Last modified January 20, 2009. Version 3.
Checksum: 88F1FEDA6BD68A3B

FASTA17719,564
        10         20         30         40         50         60 
MLQTYKDQLP DYAKDLKLNL TQVLSESPSS ELSNQQITGV ALAVAYATRN RQLIELIFQK 

        70         80         90        100        110        120 
AEAELDESTL QAIKAAASIM AMNNIYYRFV HLVKDSEYQR LPANLRMNII ANPGIDKKDF 

       130        140        150        160        170 
ELYSLAVSAI NGCGLCIDAH ANTLIKAGFS KHSIQHVIRI AAVLNGLAQV SIIENKT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO90975.2. Different initiation.
RefSeqNP_820461.2. NC_002971.3.

3D structure databases

ProteinModelPortalQ83BM5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1478.

Protein family/group databases

PeroxiBase4610. CbuAhpD_RSA493.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO90975; AAO90975; CBU_1478.
GeneID1209388.
KEGGcbu:CBU_1478.
PATRIC17931717. VBICoxBur82552_1478.

Phylogenomic databases

eggNOGCOG2128.
HOGENOMHOG000261487.
KOK04756.
OMARAGLRMN.
OrthoDBEOG6PCQ0G.
ProtClustDBCLSK914808.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1466-MONOMER.

Family and domain databases

HAMAPMF_01676. AhpD.
InterProIPR004674. AhpD.
IPR004675. AhpD_core.
IPR003779. CMD-like.
[Graphical view]
PfamPF02627. CMD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00778. ahpD_dom. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAHPD_COXBU
AccessionPrimary (citable) accession number: Q83BM5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 20, 2009
Last modified: April 16, 2014
This is version 68 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names