Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q83BJ0 (GPDA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC=1.1.1.94
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Gene names
Name:gpsA
Ordered Locus Names:CBU_1518
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella ›

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H. HAMAP-Rule MF_00394

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism. HAMAP-Rule MF_00394

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 332332Glycerol-3-phosphate dehydrogenase [NAD(P)+] HAMAP-Rule MF_00394
PRO_0000137953

Regions

Nucleotide binding12 – 176NAD By similarity
Region256 – 2572Substrate binding By similarity

Sites

Active site1921Proton acceptor By similarity
Binding site1101NAD; via amide nitrogen By similarity
Binding site1101Substrate By similarity
Binding site1411NAD; via amide nitrogen By similarity
Binding site2561NAD By similarity
Binding site2821NAD By similarity

Secondary structure

1 ........................................................ 332
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q83BJ0 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 0790551553B52A94

FASTA33236,067
        10         20         30         40         50         60 
MEPFKHPIAI LGAGSWGTAL ALVLARKGQK VRLWSYESDH VDEMQAEGVN NRYLPNYPFP 

        70         80         90        100        110        120 
ETLKAYCDLK ASLEGVTDIL IVVPSFAFHE VITRMKPLID AKTRIAWGTK GLAKGSRLLH 

       130        140        150        160        170        180 
EVVATELGQV PMAVISGPSL ATEVAANLPT AVSLASNNSQ FSKDLIERLH GQRFRVYKND 

       190        200        210        220        230        240 
DMIGVELCGS VKNILAIATG ISDGLKLGSN ARAALITRGL TEMGRLVSVF GGKQETLTGL 

       250        260        270        280        290        300 
AGLGDLVLTC TDNQSRNRRF GLALGEGVDK KEAQQAIGQA IEGLYNTDQV HALAQKHAIE 

       310        320        330 
MPLTFQVHRI LHEDLDPQQA VQELLERSPK AE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016828 Genomic DNA. Translation: AAO91015.1.
RefSeqNP_820501.1. NC_002971.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3K96X-ray2.10A/B1-332[»]
ProteinModelPortalQ83BJ0.
ModBaseSearch...

Protein-protein interaction databases

STRING227377.CBU_1518.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91015; AAO91015; CBU_1518.
GeneID1209428.
KEGGcbu:CBU_1518.
PATRIC17931803. VBICoxBur82552_1521.

Phylogenomic databases

eggNOGCOG0240.
HOGENOMHOG000246854.
KOK00057.
OMAKGIEHGT.
ProtClustDBPRK00094.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1503-MONOMER.
UniPathwayUPA00940.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00394. NAD_Glyc3P_dehydrog.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ83BJ0.

Entry information

Entry nameGPDA_COXBU
AccessionPrimary (citable) accession number: Q83BJ0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: June 1, 2003
Last modified: May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents