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Q83BE2 (RUVA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holliday junction ATP-dependent DNA helicase RuvA

EC=3.6.4.12
Gene names
Name:ruvA
Ordered Locus Names:CBU_1568
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031

Catalytic activity

ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031

Subunit structure

Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031

Sequence similarities

Belongs to the RuvA family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031
PRO_0000094627

Sequences

Sequence LengthMass (Da)Tools
Q83BE2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 1C48A1F35D1CC2DE

FASTA20022,225
        10         20         30         40         50         60 
MIGHLRGIIV EKQPPYLLLE VAGVGYEITA PLSTFYHLPE PQEEILLYTH LIVREDAHTL 

        70         80         90        100        110        120 
YGFHNDHERR LFRALIKVNG VGPKLALAIL SGIGPDEFVH CVLNQNIDQL VRIPGVGRKT 

       130        140        150        160        170        180 
AERLVIETKD GLSRWHTNDT PSPEGLRSSN TQPTQDAISA LMALGYKPQE AKRAIDAIQK 

       190        200 
PDLSAETLIR LALKQMVLGT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO91065.1.
RefSeqNP_820551.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83BE2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1568.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91065; AAO91065; CBU_1568.
GeneID1209478.
KEGGcbu:CBU_1568.
PATRIC17931899. VBICoxBur82552_1569.

Phylogenomic databases

eggNOGCOG0632.
HOGENOMHOG000057116.
KOK03550.
OMAVGYQVHC.
OrthoDBEOG679THG.
ProtClustDBPRK00116.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1547-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00031. DNA_helic_RuvA.
InterProIPR011114. DNA_helicas_Holl-junc_RuvA_C.
IPR013849. DNA_helicase_Holl-junc_RuvA_I.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR012340. NA-bd_OB-fold.
IPR000085. RuvA.
IPR010994. RuvA_2-like.
[Graphical view]
PfamPF07499. RuvA_C. 1 hit.
PF01330. RuvA_N. 1 hit.
[Graphical view]
SMARTSM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF46929. SSF46929. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00084. ruvA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRUVA_COXBU
AccessionPrimary (citable) accession number: Q83BE2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names