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Q83BE0 (RUVB_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holliday junction ATP-dependent DNA helicase RuvB

EC=3.6.4.12
Gene names
Name:ruvB
Ordered Locus Names:CBU_1570
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing By similarity. HAMAP-Rule MF_00016

Catalytic activity

ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00016

Subunit structure

Forms a complex with RuvA By similarity. HAMAP-Rule MF_00016

Sequence similarities

Belongs to the RuvB family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 351351Holliday junction ATP-dependent DNA helicase RuvB HAMAP-Rule MF_00016
PRO_0000165525

Regions

Nucleotide binding64 – 718ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q83BE0 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 7A69DB0B71CC72FF

FASTA35139,151
        10         20         30         40         50         60 
MDEKIETRLI GATVQSNEPD LERSIRPKRL SDYIGQAAVR EQMDIFIRAA TNRREALDHV 

        70         80         90        100        110        120 
LIFGPPGLGK TTLAHIIAHE MQAGLKQTSG PVLEKAGDLA ALLTNLEPHD VLFIDEIHRL 

       130        140        150        160        170        180 
NPAIEEVLYP ALEDFQLDII IGEGPSARSI KLDLPPFTLV GATTRAGLLT SPLRDRFGIV 

       190        200        210        220        230        240 
QRLEFYRIPD LIHIVKRAAH ILNVVIDENG AGEIARRSRG TPRIANRLLR RVRDFAEVRA 

       250        260        270        280        290        300 
NGMINESIAK EALDLLNVDI RGLDVMDRKL LETIIKKFQG GPVGIESLAA AISEERGTIE 

       310        320        330        340        350 
DVIEPYLIQE GFILRTPRGR IATELTYQHF KLPLPTQSTL QENFDLLGKV E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO91067.1.
RefSeqNP_820553.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83BE0.
SMRQ83BE0. Positions 24-336.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1570.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91067; AAO91067; CBU_1570.
GeneID1209480.
KEGGcbu:CBU_1570.
PATRIC17931903. VBICoxBur82552_1571.

Phylogenomic databases

eggNOGCOG2255.
HOGENOMHOG000218623.
KOK03551.
OMANGYLERT.
OrthoDBEOG6SR93S.
ProtClustDBPRK00080.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1549-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
3.40.50.300. 2 hits.
HAMAPMF_00016. DNA_helic_RuvB.
InterProIPR003593. AAA+_ATPase.
IPR004605. DNA_helicase_Holl-junc_RuvB.
IPR008823. DNA_helicase_Holl-junc_RuvB_C.
IPR008824. DNA_helicase_Holl-junc_RuvB_N.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF05491. RuvB_C. 1 hit.
PF05496. RuvB_N. 1 hit.
[Graphical view]
ProDomPD005323. DNA_helicase_Holl-junc_RuvB_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00635. ruvB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRUVB_COXBU
AccessionPrimary (citable) accession number: Q83BE0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names