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Q83B43

- KDSA_COXBU

UniProt

Q83B43 - KDSA_COXBU

Protein

2-dehydro-3-deoxyphosphooctonate aldolase

Gene

kdsA

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-deoxy-8-phosphooctulonate synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciCBUR227377:GJ7S-1646-MONOMER.
    UniPathwayiUPA00030.
    UPA00357; UER00474.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)
    Alternative name(s):
    3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation
    KDO-8-phosphate synthaseUniRule annotation
    Short name:
    KDO 8-P synthaseUniRule annotation
    Short name:
    KDOPSUniRule annotation
    Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation
    Gene namesi
    Name:kdsAUniRule annotation
    Ordered Locus Names:CBU_1675
    OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
    Taxonomic identifieri227377 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
    ProteomesiUP000002671: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2802802-dehydro-3-deoxyphosphooctonate aldolasePRO_0000187121Add
    BLAST

    Proteomic databases

    PRIDEiQ83B43.

    Interactioni

    Protein-protein interaction databases

    STRINGi227377.CBU_1675.

    Structurei

    3D structure databases

    ProteinModelPortaliQ83B43.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KdsA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2877.
    HOGENOMiHOG000023021.
    KOiK01627.
    OMAiMESREHA.
    OrthoDBiEOG680X4R.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00056. KDO8P_synth.
    InterProiIPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view]
    PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
    PfamiPF00793. DAHP_synth_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q83B43-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLMQIADFEI GLNNPLFLIA GPCVIESEAL VMDVAGELKS ITQQLDMPFI    50
    FKASFDKANR SSHLSYRGPG IEKGLTILEK VKKTLEVPII TDVHEDTPLQ 100
    EVAAVVDVLQ TPAFLCRQSN FIRSVAACGK PVNIKKGQFL APWEMKQVVA 150
    KAWATGNKKI MVCERGYSFG YNNLISDMRA LAILRETACP VIFDATHSVQ 200
    LPGGHGTNSG GQREFVPVLA RAATAAGIAG IFMETHPDPD RALSDGPNSW 250
    PLAKMQPLLE TLKELDKVVK NAGFLEQSSE 280
    Length:280
    Mass (Da):30,507
    Last modified:June 1, 2003 - v1
    Checksum:i56B00DBDEAC19389
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAO91171.1.
    RefSeqiNP_820657.1. NC_002971.3.

    Genome annotation databases

    EnsemblBacteriaiAAO91171; AAO91171; CBU_1675.
    GeneIDi1209586.
    KEGGicbu:CBU_1675.
    PATRICi17932091. VBICoxBur82552_1664.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAO91171.1 .
    RefSeqi NP_820657.1. NC_002971.3.

    3D structure databases

    ProteinModelPortali Q83B43.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227377.CBU_1675.

    Proteomic databases

    PRIDEi Q83B43.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO91171 ; AAO91171 ; CBU_1675 .
    GeneIDi 1209586.
    KEGGi cbu:CBU_1675.
    PATRICi 17932091. VBICoxBur82552_1664.

    Phylogenomic databases

    eggNOGi COG2877.
    HOGENOMi HOG000023021.
    KOi K01627.
    OMAi MESREHA.
    OrthoDBi EOG680X4R.

    Enzyme and pathway databases

    UniPathwayi UPA00030 .
    UPA00357 ; UER00474 .
    BioCyci CBUR227377:GJ7S-1646-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00056. KDO8P_synth.
    InterProi IPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view ]
    PANTHERi PTHR21057:SF2. PTHR21057:SF2. 1 hit.
    Pfami PF00793. DAHP_synth_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01362. KDO8P_synth. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RSA 493 / Nine Mile phase I.

    Entry informationi

    Entry nameiKDSA_COXBU
    AccessioniPrimary (citable) accession number: Q83B43
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 24, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Coxiella burnetii
      Coxiella burnetii (strain RSA 493): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3