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Q83AQ4

- PSD_COXBU

UniProt

Q83AQ4 - PSD_COXBU

Protein

Phosphatidylserine decarboxylase proenzyme

Gene

psd

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Phosphatidyl-L-serine = phosphatidylethanolamine + CO2.UniRule annotation

    Cofactori

    Pyruvoyl group.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei243 – 2442Cleavage (non-hydrolytic)UniRule annotation

    GO - Molecular functioni

    1. phosphatidylserine decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. phosphatidylethanolamine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Keywords - Ligandi

    Pyruvate

    Enzyme and pathway databases

    BioCyciCBUR227377:GJ7S-1799-MONOMER.
    UniPathwayiUPA00558; UER00616.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylserine decarboxylase proenzymeUniRule annotation (EC:4.1.1.65UniRule annotation)
    Cleaved into the following 2 chains:
    Phosphatidylserine decarboxylase alpha chainUniRule annotation
    Phosphatidylserine decarboxylase beta chainUniRule annotation
    Gene namesi
    Name:psdUniRule annotation
    Ordered Locus Names:CBU_1826
    OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
    Taxonomic identifieri227377 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
    ProteomesiUP000002671: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 243243Phosphatidylserine decarboxylase beta chainUniRule annotationPRO_0000029645Add
    BLAST
    Chaini244 – 28239Phosphatidylserine decarboxylase alpha chainUniRule annotationPRO_0000029646Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei244 – 2441Pyruvic acid (Ser)UniRule annotation

    Keywords - PTMi

    Zymogen

    Interactioni

    Protein-protein interaction databases

    STRINGi227377.CBU_1826.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0688.
    HOGENOMiHOG000282407.
    KOiK01613.
    OMAiTWEYPTV.
    OrthoDBiEOG6B8XK4.

    Family and domain databases

    HAMAPiMF_00662. PS_decarb_type1.
    InterProiIPR003817. PS_Dcarbxylase.
    IPR005221. PS_decarb.
    [Graphical view]
    PANTHERiPTHR10067. PTHR10067. 1 hit.
    PfamiPF02666. PS_Dcarbxylase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00163. PS_decarb. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q83AQ4-1 [UniParc]FASTAAdd to Basket

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    MTKLHKYLPQ RTLSKIVGWL ATREWGLLTQ WAIRLFIRHY GINMQEAQYP    50
    DIGHYPSFNA FFTRYLKREL RPVVEEPRAI ASPVDGIISE MGQIKGENLI 100
    QAKNHHYTIT ALLGEDPSRA SQFLDGDFFT AYLAPKNYHR IHMPLDGRLI 150
    EMIHIPGKLF SVNPASVQTV PRLFARNERA VCLFETENGL MAVILVGAML 200
    VGSINTVWHG TVVPTAEGIA VHNYREKNIK FKRGEEIGHF KMGSTVILLF 250
    PKNTIQWNPN CQPKGTICYG ENIGTVSLIE VA 282
    Length:282
    Mass (Da):31,941
    Last modified:June 1, 2003 - v1
    Checksum:iA7416445E271A8A7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAO91319.1.
    RefSeqiNP_820805.1. NC_002971.3.

    Genome annotation databases

    EnsemblBacteriaiAAO91319; AAO91319; CBU_1826.
    GeneIDi1209737.
    KEGGicbu:CBU_1826.
    PATRICi17932383. VBICoxBur82552_1810.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAO91319.1 .
    RefSeqi NP_820805.1. NC_002971.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227377.CBU_1826.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO91319 ; AAO91319 ; CBU_1826 .
    GeneIDi 1209737.
    KEGGi cbu:CBU_1826.
    PATRICi 17932383. VBICoxBur82552_1810.

    Phylogenomic databases

    eggNOGi COG0688.
    HOGENOMi HOG000282407.
    KOi K01613.
    OMAi TWEYPTV.
    OrthoDBi EOG6B8XK4.

    Enzyme and pathway databases

    UniPathwayi UPA00558 ; UER00616 .
    BioCyci CBUR227377:GJ7S-1799-MONOMER.

    Family and domain databases

    HAMAPi MF_00662. PS_decarb_type1.
    InterProi IPR003817. PS_Dcarbxylase.
    IPR005221. PS_decarb.
    [Graphical view ]
    PANTHERi PTHR10067. PTHR10067. 1 hit.
    Pfami PF02666. PS_Dcarbxylase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00163. PS_decarb. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RSA 493 / Nine Mile phase I.

    Entry informationi

    Entry nameiPSD_COXBU
    AccessioniPrimary (citable) accession number: Q83AQ4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 3, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Coxiella burnetii
      Coxiella burnetii (strain RSA 493): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3