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Q83AL3 (COQ7_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

EC=1.14.13.-
Alternative name(s):
5-demethoxyubiquinone hydroxylase
Short name=DMQ hydroxylase
Gene names
Name:coq7
Ordered Locus Names:CBU_1870
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol By similarity. HAMAP-Rule MF_01658

Cofactor

Binds 2 iron ions per subunit By similarity. HAMAP-Rule MF_01658

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP-Rule MF_01658

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01658.

Sequence similarities

Belongs to the COQ7 family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCell membrane
Membrane
   LigandIron
Metal-binding
   Molecular functionMonooxygenase
Oxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein metabolic process

Inferred from electronic annotation. Source: InterPro

ubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

monooxygenase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2152152-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase HAMAP-Rule MF_01658
PRO_0000338680

Sites

Metal binding641Iron 1 By similarity
Metal binding941Iron 1 By similarity
Metal binding941Iron 2 By similarity
Metal binding971Iron 1 By similarity
Metal binding1461Iron 2 By similarity
Metal binding1781Iron 1 By similarity
Metal binding1781Iron 2 By similarity
Metal binding1811Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q83AL3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 05A407060CD072B9

FASTA21523,935
        10         20         30         40         50         60 
MSNNSRHYSA IDEAILQGQA MLETLFGKPV AQRENPAKGL SQPALTSAEK KQSIGFMRVN 

        70         80         90        100        110        120 
HSGEVCAQAL YHGQMATAKN PAVRALFTTA AKEETDHLAW CQERLEELGG HTSYLNAFWY 

       130        140        150        160        170        180 
TNSFLIGLLA GLSGDPLSLG FVEETEKQVE IHLADHLRKI PSNDLKSRKI VEYMQQDEIQ 

       190        200        210 
HGLNARSSGA KELPYLVKKL MAFQAKVMTT LAYWI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO91361.1.
RefSeqNP_820847.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83AL3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1870.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91361; AAO91361; CBU_1870.
GeneID1209783.
KEGGcbu:CBU_1870.
PATRIC17932471. VBICoxBur82552_1852.

Phylogenomic databases

eggNOGCOG2941.
HOGENOMHOG000237383.
KOK06134.
OMAHESRAIV.
OrthoDBEOG6VB6TN.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1846-MONOMER.
UniPathwayUPA00232.

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
HAMAPMF_01658. COQ7.
InterProIPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR011566. Ubq_synth_Coq7.
IPR023782. Ubq_synth_Coq7_bac.
[Graphical view]
PANTHERPTHR11237. PTHR11237. 1 hit.
PfamPF03232. COQ7. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOQ7_COXBU
AccessionPrimary (citable) accession number: Q83AL3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names