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Protein

2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Gene

coq7

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol.UniRule annotation

Cofactori

Fe cationUniRule annotationNote: Binds 2 iron ions per subunit.UniRule annotation

Pathway: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi64 – 641Iron 1UniRule annotation
Metal bindingi94 – 941Iron 1UniRule annotation
Metal bindingi94 – 941Iron 2UniRule annotation
Metal bindingi97 – 971Iron 1UniRule annotation
Metal bindingi146 – 1461Iron 2UniRule annotation
Metal bindingi178 – 1781Iron 1UniRule annotation
Metal bindingi178 – 1781Iron 2UniRule annotation
Metal bindingi181 – 1811Iron 2UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1846-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylaseUniRule annotation (EC:1.14.13.-UniRule annotation)
Alternative name(s):
5-demethoxyubiquinone hydroxylaseUniRule annotation
Short name:
DMQ hydroxylaseUniRule annotation
Gene namesi
Name:coq7UniRule annotation
Ordered Locus Names:CBU_1870
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002671 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2152152-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylasePRO_0000338680Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1870.

Structurei

3D structure databases

ProteinModelPortaliQ83AL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the COQ7 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2941.
HOGENOMiHOG000237383.
KOiK06134.
OMAiTRTAYWV.
OrthoDBiEOG6VB6TN.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
HAMAPiMF_01658. COQ7.
InterProiIPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR011566. Ubq_synth_Coq7.
IPR023782. Ubq_synth_Coq7_bac.
[Graphical view]
PANTHERiPTHR11237. PTHR11237. 1 hit.
PfamiPF03232. COQ7. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.

Sequencei

Sequence statusi: Complete.

Q83AL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNSRHYSA IDEAILQGQA MLETLFGKPV AQRENPAKGL SQPALTSAEK
60 70 80 90 100
KQSIGFMRVN HSGEVCAQAL YHGQMATAKN PAVRALFTTA AKEETDHLAW
110 120 130 140 150
CQERLEELGG HTSYLNAFWY TNSFLIGLLA GLSGDPLSLG FVEETEKQVE
160 170 180 190 200
IHLADHLRKI PSNDLKSRKI VEYMQQDEIQ HGLNARSSGA KELPYLVKKL
210
MAFQAKVMTT LAYWI
Length:215
Mass (Da):23,935
Last modified:June 1, 2003 - v1
Checksum:i05A407060CD072B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO91361.1.
RefSeqiNP_820847.1. NC_002971.3.
WP_010958504.1. NC_002971.3.

Genome annotation databases

EnsemblBacteriaiAAO91361; AAO91361; CBU_1870.
GeneIDi1209783.
KEGGicbu:CBU_1870.
PATRICi17932471. VBICoxBur82552_1852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA. Translation: AAO91361.1.
RefSeqiNP_820847.1. NC_002971.3.
WP_010958504.1. NC_002971.3.

3D structure databases

ProteinModelPortaliQ83AL3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227377.CBU_1870.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO91361; AAO91361; CBU_1870.
GeneIDi1209783.
KEGGicbu:CBU_1870.
PATRICi17932471. VBICoxBur82552_1852.

Phylogenomic databases

eggNOGiCOG2941.
HOGENOMiHOG000237383.
KOiK06134.
OMAiTRTAYWV.
OrthoDBiEOG6VB6TN.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciCBUR227377:GJ7S-1846-MONOMER.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
HAMAPiMF_01658. COQ7.
InterProiIPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR011566. Ubq_synth_Coq7.
IPR023782. Ubq_synth_Coq7_bac.
[Graphical view]
PANTHERiPTHR11237. PTHR11237. 1 hit.
PfamiPF03232. COQ7. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 493 / Nine Mile phase I.

Entry informationi

Entry nameiCOQ7_COXBU
AccessioniPrimary (citable) accession number: Q83AL3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 1, 2003
Last modified: May 27, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.