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Q83AJ3 (AROK_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate kinase
Short name=SK
EC=2.7.1.71
Gene names
Name:aroK
Ordered Locus Names:CBU_1892
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella ›

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP-Rule MF_00109

Catalytic activity

ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP-Rule MF_00109

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP-Rule MF_00109

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the shikimate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 179179Shikimate kinase HAMAP-Rule MF_00109
PRO_0000237869

Regions

Nucleotide binding15 – 206ATP By similarity

Sites

Metal binding191Magnesium By similarity
Binding site371Substrate By similarity
Binding site611Substrate By similarity
Binding site831Substrate; via amide nitrogen By similarity
Binding site1231ATP By similarity
Binding site1421Substrate By similarity

Secondary structure

1 .......................... 179
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q83AJ3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: A47C31B7EF35941C

FASTA17920,335
        10         20         30         40         50         60 
MKKNLTNIYL IGLMGAGKTS VGSQLAKLTK RILYDSDKEI EKRTGADIAW IFEMEGEAGF 

        70         80         90        100        110        120 
RRREREMIEA LCKLDNIILA TGGGVVLDEK NRQQISETGV VIYLTASIDT QLKRIGQKGE 

       130        140        150        160        170 
MRRPLFIKNN SKEKLQQLNE IRKPLYQAMA DLVYPTDDLN PRQLATQILV DIKQTYSDL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016828 Genomic DNA. Translation: AAO91383.1.
RefSeqNP_820869.1. NC_002971.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3TRFX-ray2.60A/B1-179[»]
ProteinModelPortalQ83AJ3.
ModBaseSearch...

Protein-protein interaction databases

STRING227377.CBU_1892.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91383; AAO91383; CBU_1892.
GeneID1209805.
KEGGcbu:CBU_1892.
PATRIC17932517. VBICoxBur82552_1875.

Phylogenomic databases

eggNOGCOG0703.
HOGENOMHOG000032568.
KOK00891.
OMAADIPWIF.
ProtClustDBCLSK915106.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1867-MONOMER.
UniPathwayUPA00053; UER00088.

Family and domain databases

HAMAPMF_00109. Shikimate_kinase.
InterProIPR000623. Shikimate_kinase.
IPR023000. Shikimate_kinase_CS.
[Graphical view]
PfamPF01202. SKI. 1 hit.
[Graphical view]
PRINTSPR01100. SHIKIMTKNASE.
PROSITEPS01128. SHIKIMATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ83AJ3.

Entry information

Entry nameAROK_COXBU
AccessionPrimary (citable) accession number: Q83AJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2003
Last modified: May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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