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Q83AB7 (APAH_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

EC=3.6.1.41
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene names
Name:apaH
Ordered Locus Names:CBU_1987
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity. HAMAP-Rule MF_00199

Catalytic activity

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP-Rule MF_00199

Sequence similarities

Belongs to the Ap4A hydrolase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 291291Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP-Rule MF_00199
PRO_0000197987

Sequences

Sequence LengthMass (Da)Tools
Q83AB7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 27FB606C6A0D9765

FASTA29133,300
        10         20         30         40         50         60 
MDARAINSRE KADLKYPRNT YIIGDVQGCY RELQELLELI QFDSTKDRLG FVGDLVNRGP 

        70         80         90        100        110        120 
NSLEVLRFLK SLSSPLIVLG NHDLYLLILG YGLMPEDSYE HTLHAVLQAP DKLELLEWLR 

       130        140        150        160        170        180 
HSPLIRYEKS LSAVLVHAGL PPQWNIKESI LHAEEISTAL KGPHYLAFLK NLFGNEPSQW 

       190        200        210        220        230        240 
KEDLEGQDRL RYICNAFTRM RFCDAKGHLD LESEGKTNQA PSRFRPWFEW RNPQEDNVDI 

       250        260        270        280        290 
VFGHWAALNG QSSAPHTHAL DTGCAWGYKL TAINLKTKER FSVPCQSALR M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAO91476.1.
RefSeqNP_820962.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ83AB7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1987.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91476; AAO91476; CBU_1987.
GeneID1209900.
KEGGcbu:CBU_1987.
PATRIC17932715. VBICoxBur82552_1974.

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000251871.
KOK01525.
OMAWLRHQPL.
OrthoDBEOG66B3WP.
ProtClustDBPRK00166.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1960-MONOMER.

Family and domain databases

HAMAPMF_00199. ApaH.
InterProIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF000903. B5n-ttraPtase_sm. 1 hit.
TIGRFAMsTIGR00668. apaH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPAH_COXBU
AccessionPrimary (citable) accession number: Q83AB7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names